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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDCD6IP All Species: 38.48
Human Site: S481 Identified Species: 60.48
UniProt: Q8WUM4 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WUM4 NP_037506.2 868 96023 S481 E R W Q R T P S N E L Y K P L
Chimpanzee Pan troglodytes XP_001169526 868 96035 S481 E R W Q R T P S N E L Y K P L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534215 869 96105 S481 E R W Q R T P S N E L Y K P L
Cat Felis silvestris
Mouse Mus musculus Q9WU78 869 95992 S481 D R W Q R T P S N D L Y K P L
Rat Rattus norvegicus Q9QZA2 873 96612 S486 D R W Q R T P S N D L Y K P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520983 801 88429 F427 L R A E G N N F R A V L D K A
Chicken Gallus gallus NP_001026164 882 97297 S485 E R W Q R T P S N D L Y K P L
Frog Xenopus laevis Q9W6C5 867 96180 S480 D R W Q R T P S T E L Y K P L
Zebra Danio Brachydanio rerio NP_998525 866 95753 S478 Q R W N R T P S G D L Y K P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651582 836 92520 I453 L L N R N R E I L D E T E R L
Honey Bee Apis mellifera XP_396117 816 91664 L440 M K E L P D L L Q R N K E L L
Nematode Worm Caenorhab. elegans P34552 882 98246 S488 T K W T R M S S E Q L T G P L
Sea Urchin Strong. purpuratus XP_001204017 886 97596 S483 E K W T R V P S D Q L T T A L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12033 661 75929 K287 T V V E S S L K E A Q R D N E
Red Bread Mold Neurospora crassa Q7SAN9 1012 112176 S498 A E W T Q Q P S S R L T T T L
Conservation
Percent
Protein Identity: 100 99.8 N.A. 97 N.A. 94.2 94.1 N.A. 81.6 83.9 76.9 73.1 N.A. 42.2 43 39.2 46.3
Protein Similarity: 100 99.8 N.A. 97.9 N.A. 96.6 96.3 N.A. 85.7 90.6 88.8 85 N.A. 60.9 60.9 57.2 63.8
P-Site Identity: 100 100 N.A. 100 N.A. 86.6 86.6 N.A. 6.6 93.3 86.6 73.3 N.A. 6.6 6.6 40 46.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 20 100 93.3 86.6 N.A. 26.6 20 53.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.1 29.5
Protein Similarity: N.A. N.A. N.A. N.A. 40.3 44
P-Site Identity: N.A. N.A. N.A. N.A. 0 33.3
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 0 0 0 0 0 0 14 0 0 0 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 20 0 0 0 0 7 0 0 7 34 0 0 14 0 0 % D
% Glu: 34 7 7 14 0 0 7 0 14 27 7 0 14 0 7 % E
% Phe: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 7 0 0 0 7 0 0 0 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % I
% Lys: 0 20 0 0 0 0 0 7 0 0 0 7 54 7 0 % K
% Leu: 14 7 0 7 0 0 14 7 7 0 74 7 0 7 87 % L
% Met: 7 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 7 7 7 7 0 40 0 7 0 0 7 0 % N
% Pro: 0 0 0 0 7 0 67 0 0 0 0 0 0 60 0 % P
% Gln: 7 0 0 47 7 7 0 0 7 14 7 0 0 0 0 % Q
% Arg: 0 60 0 7 67 7 0 0 7 14 0 7 0 7 0 % R
% Ser: 0 0 0 0 7 7 7 74 7 0 0 0 0 0 0 % S
% Thr: 14 0 0 20 0 54 0 0 7 0 0 27 14 7 0 % T
% Val: 0 7 7 0 0 7 0 0 0 0 7 0 0 0 0 % V
% Trp: 0 0 74 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 54 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _