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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDCD6IP
All Species:
18.18
Human Site:
S557
Identified Species:
28.57
UniProt:
Q8WUM4
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUM4
NP_037506.2
868
96023
S557
N
V
L
K
S
L
L
S
N
L
D
E
V
K
K
Chimpanzee
Pan troglodytes
XP_001169526
868
96035
S557
N
V
L
K
S
L
L
S
N
L
D
E
V
K
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534215
869
96105
T557
N
V
L
K
S
L
L
T
N
L
D
E
V
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU78
869
95992
S557
S
V
L
K
S
L
L
S
N
L
D
E
I
K
K
Rat
Rattus norvegicus
Q9QZA2
873
96612
S562
N
V
L
K
S
L
L
S
N
L
D
E
I
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520983
801
88429
N500
E
V
K
K
E
R
E
N
L
E
N
D
L
K
S
Chicken
Gallus gallus
NP_001026164
882
97297
A561
N
V
L
K
T
L
L
A
S
L
D
E
V
K
K
Frog
Xenopus laevis
Q9W6C5
867
96180
N556
T
V
L
K
S
L
L
N
K
L
D
D
M
K
K
Zebra Danio
Brachydanio rerio
NP_998525
866
95753
A554
N
V
L
R
S
Q
L
A
Q
L
D
E
V
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651582
836
92520
L528
K
G
I
Q
L
L
S
L
P
P
D
Q
I
Q
Q
Honey Bee
Apis mellifera
XP_396117
816
91664
K513
R
E
K
Y
E
N
H
K
E
G
I
E
I
L
S
Nematode Worm
Caenorhab. elegans
P34552
882
98246
Q564
Q
L
R
Q
F
M
S
Q
W
N
E
V
T
T
D
Sea Urchin
Strong. purpuratus
XP_001204017
886
97596
K559
Q
E
L
R
Q
L
M
K
D
V
D
E
I
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12033
661
75929
V360
D
E
Y
V
E
Q
R
V
T
N
P
L
A
S
L
Red Bread Mold
Neurospora crassa
Q7SAN9
1012
112176
L603
D
I
L
K
K
L
S
L
V
K
K
E
R
L
Q
Conservation
Percent
Protein Identity:
100
99.8
N.A.
97
N.A.
94.2
94.1
N.A.
81.6
83.9
76.9
73.1
N.A.
42.2
43
39.2
46.3
Protein Similarity:
100
99.8
N.A.
97.9
N.A.
96.6
96.3
N.A.
85.7
90.6
88.8
85
N.A.
60.9
60.9
57.2
63.8
P-Site Identity:
100
100
N.A.
93.3
N.A.
86.6
93.3
N.A.
20
80
66.6
66.6
N.A.
13.3
6.6
0
33.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
46.6
100
86.6
86.6
N.A.
53.3
13.3
26.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.1
29.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.3
44
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
14
0
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
0
0
0
0
0
0
0
7
0
67
14
0
0
7
% D
% Glu:
7
20
0
0
20
0
7
0
7
7
7
67
0
0
0
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
7
0
0
0
0
0
0
0
7
0
34
0
0
% I
% Lys:
7
0
14
60
7
0
0
14
7
7
7
0
0
67
47
% K
% Leu:
0
7
67
0
7
67
54
14
7
54
0
7
7
14
7
% L
% Met:
0
0
0
0
0
7
7
0
0
0
0
0
7
0
0
% M
% Asn:
40
0
0
0
0
7
0
14
34
14
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
7
7
0
0
0
0
% P
% Gln:
14
0
0
14
7
14
0
7
7
0
0
7
0
7
14
% Q
% Arg:
7
0
7
14
0
7
7
0
0
0
0
0
7
0
7
% R
% Ser:
7
0
0
0
47
0
20
27
7
0
0
0
0
7
14
% S
% Thr:
7
0
0
0
7
0
0
7
7
0
0
0
7
7
7
% T
% Val:
0
60
0
7
0
0
0
7
7
7
0
7
34
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _