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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDCD6IP All Species: 35.45
Human Site: S575 Identified Species: 55.71
UniProt: Q8WUM4 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WUM4 NP_037506.2 868 96023 S575 G L E N D L K S V N F D M T S
Chimpanzee Pan troglodytes XP_001169526 868 96035 S575 G L E N D L K S V N F D M T S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534215 869 96105 S575 G L E N D L K S V N F D M T S
Cat Felis silvestris
Mouse Mus musculus Q9WU78 869 95992 S575 S L E N D L K S V N F D M T S
Rat Rattus norvegicus Q9QZA2 873 96612 S580 G L E N D L K S V N F D M T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520983 801 88429 K515 V N F D M T S K F L T S L A Q
Chicken Gallus gallus NP_001026164 882 97297 S579 Q L E N D L K S V N F D M T N
Frog Xenopus laevis Q9W6C5 867 96180 S574 Q L E N D I K S V N F D M T T
Zebra Danio Brachydanio rerio NP_998525 866 95753 S572 V L E G E V K S V T F D L T A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651582 836 92520 S543 S L P S A S G S V D P N C S S
Honey Bee Apis mellifera XP_396117 816 91664 N528 L N E N D L I N A V P T G S A
Nematode Worm Caenorhab. elegans P34552 882 98246 N581 L L E K E L K N T N C D I A N
Sea Urchin Strong. purpuratus XP_001204017 886 97596 S577 V L E N E I K S A T V D I K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12033 661 75929 L375 N K L L K E S L T T F Q I P Q
Red Bread Mold Neurospora crassa Q7SAN9 1012 112176 K618 V L Q D L K Q K A H S D D I S
Conservation
Percent
Protein Identity: 100 99.8 N.A. 97 N.A. 94.2 94.1 N.A. 81.6 83.9 76.9 73.1 N.A. 42.2 43 39.2 46.3
Protein Similarity: 100 99.8 N.A. 97.9 N.A. 96.6 96.3 N.A. 85.7 90.6 88.8 85 N.A. 60.9 60.9 57.2 63.8
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 100 N.A. 0 86.6 80 53.3 N.A. 26.6 26.6 40 46.6
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 100 N.A. 13.3 93.3 93.3 80 N.A. 53.3 46.6 66.6 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.1 29.5
Protein Similarity: N.A. N.A. N.A. N.A. 40.3 44
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 20
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 0 0 0 20 0 0 0 0 14 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 7 0 7 0 0 % C
% Asp: 0 0 0 14 54 0 0 0 0 7 0 74 7 0 0 % D
% Glu: 0 0 74 0 20 7 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 7 0 0 0 0 0 7 0 60 0 0 0 0 % F
% Gly: 27 0 0 7 0 0 7 0 0 0 0 0 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 14 7 0 0 0 0 0 20 7 0 % I
% Lys: 0 7 0 7 7 7 67 14 0 0 0 0 0 7 0 % K
% Leu: 14 80 7 7 7 54 0 7 0 7 0 0 14 0 0 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 47 0 0 % M
% Asn: 7 14 0 60 0 0 0 14 0 54 0 7 0 0 14 % N
% Pro: 0 0 7 0 0 0 0 0 0 0 14 0 0 7 0 % P
% Gln: 14 0 7 0 0 0 7 0 0 0 0 7 0 0 14 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 14 0 0 7 0 7 14 67 0 0 7 7 0 14 54 % S
% Thr: 0 0 0 0 0 7 0 0 14 20 7 7 0 54 7 % T
% Val: 27 0 0 0 0 7 0 0 60 7 7 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _