KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDCD6IP
All Species:
35.45
Human Site:
S575
Identified Species:
55.71
UniProt:
Q8WUM4
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUM4
NP_037506.2
868
96023
S575
G
L
E
N
D
L
K
S
V
N
F
D
M
T
S
Chimpanzee
Pan troglodytes
XP_001169526
868
96035
S575
G
L
E
N
D
L
K
S
V
N
F
D
M
T
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534215
869
96105
S575
G
L
E
N
D
L
K
S
V
N
F
D
M
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU78
869
95992
S575
S
L
E
N
D
L
K
S
V
N
F
D
M
T
S
Rat
Rattus norvegicus
Q9QZA2
873
96612
S580
G
L
E
N
D
L
K
S
V
N
F
D
M
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520983
801
88429
K515
V
N
F
D
M
T
S
K
F
L
T
S
L
A
Q
Chicken
Gallus gallus
NP_001026164
882
97297
S579
Q
L
E
N
D
L
K
S
V
N
F
D
M
T
N
Frog
Xenopus laevis
Q9W6C5
867
96180
S574
Q
L
E
N
D
I
K
S
V
N
F
D
M
T
T
Zebra Danio
Brachydanio rerio
NP_998525
866
95753
S572
V
L
E
G
E
V
K
S
V
T
F
D
L
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651582
836
92520
S543
S
L
P
S
A
S
G
S
V
D
P
N
C
S
S
Honey Bee
Apis mellifera
XP_396117
816
91664
N528
L
N
E
N
D
L
I
N
A
V
P
T
G
S
A
Nematode Worm
Caenorhab. elegans
P34552
882
98246
N581
L
L
E
K
E
L
K
N
T
N
C
D
I
A
N
Sea Urchin
Strong. purpuratus
XP_001204017
886
97596
S577
V
L
E
N
E
I
K
S
A
T
V
D
I
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12033
661
75929
L375
N
K
L
L
K
E
S
L
T
T
F
Q
I
P
Q
Red Bread Mold
Neurospora crassa
Q7SAN9
1012
112176
K618
V
L
Q
D
L
K
Q
K
A
H
S
D
D
I
S
Conservation
Percent
Protein Identity:
100
99.8
N.A.
97
N.A.
94.2
94.1
N.A.
81.6
83.9
76.9
73.1
N.A.
42.2
43
39.2
46.3
Protein Similarity:
100
99.8
N.A.
97.9
N.A.
96.6
96.3
N.A.
85.7
90.6
88.8
85
N.A.
60.9
60.9
57.2
63.8
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
100
N.A.
0
86.6
80
53.3
N.A.
26.6
26.6
40
46.6
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
100
N.A.
13.3
93.3
93.3
80
N.A.
53.3
46.6
66.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.1
29.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.3
44
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
20
0
0
0
0
14
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% C
% Asp:
0
0
0
14
54
0
0
0
0
7
0
74
7
0
0
% D
% Glu:
0
0
74
0
20
7
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
7
0
0
0
0
0
7
0
60
0
0
0
0
% F
% Gly:
27
0
0
7
0
0
7
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
14
7
0
0
0
0
0
20
7
0
% I
% Lys:
0
7
0
7
7
7
67
14
0
0
0
0
0
7
0
% K
% Leu:
14
80
7
7
7
54
0
7
0
7
0
0
14
0
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
47
0
0
% M
% Asn:
7
14
0
60
0
0
0
14
0
54
0
7
0
0
14
% N
% Pro:
0
0
7
0
0
0
0
0
0
0
14
0
0
7
0
% P
% Gln:
14
0
7
0
0
0
7
0
0
0
0
7
0
0
14
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
14
0
0
7
0
7
14
67
0
0
7
7
0
14
54
% S
% Thr:
0
0
0
0
0
7
0
0
14
20
7
7
0
54
7
% T
% Val:
27
0
0
0
0
7
0
0
60
7
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _