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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDCD6IP All Species: 25.15
Human Site: Y727 Identified Species: 39.52
UniProt: Q8WUM4 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WUM4 NP_037506.2 868 96023 Y727 P S I P T P A Y Q S S P A G G
Chimpanzee Pan troglodytes XP_001169526 868 96035 Y727 P S I P T P A Y Q S S P A G G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534215 869 96105 Y727 P S I P T P A Y Q S S P A G G
Cat Felis silvestris
Mouse Mus musculus Q9WU78 869 95992 Y727 P S I P P P A Y Q S S P A A G
Rat Rattus norvegicus Q9QZA2 873 96612 Y732 P S I P P P A Y Q S S P A G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520983 801 88429 G666 Y Q A T P A G G S A S T P P T
Chicken Gallus gallus NP_001026164 882 97297 Y731 P S I P L P T Y Q T T P A G G
Frog Xenopus laevis Q9W6C5 867 96180 S726 P S I P Q V P S Y Q S A P S S
Zebra Danio Brachydanio rerio NP_998525 866 95753 Y724 P S F S V P S Y Q S N T P A P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651582 836 92520 R698 I S D F V F A R K T E K E E L
Honey Bee Apis mellifera XP_396117 816 91664 Q679 T Q L L V V F Q N K I S D F C
Nematode Worm Caenorhab. elegans P34552 882 98246 N733 K A V V D G V N S L V S S Y L
Sea Urchin Strong. purpuratus XP_001204017 886 97596 H729 A A P S A P T H H S S G Q R V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12033 661 75929 P526 S S E Y R I L P K I I T S Y K
Red Bread Mold Neurospora crassa Q7SAN9 1012 112176 R776 H A A L E Q E R L K N L M E R
Conservation
Percent
Protein Identity: 100 99.8 N.A. 97 N.A. 94.2 94.1 N.A. 81.6 83.9 76.9 73.1 N.A. 42.2 43 39.2 46.3
Protein Similarity: 100 99.8 N.A. 97.9 N.A. 96.6 96.3 N.A. 85.7 90.6 88.8 85 N.A. 60.9 60.9 57.2 63.8
P-Site Identity: 100 100 N.A. 100 N.A. 86.6 93.3 N.A. 6.6 73.3 33.3 40 N.A. 13.3 0 0 20
P-Site Similarity: 100 100 N.A. 100 N.A. 86.6 93.3 N.A. 13.3 86.6 33.3 53.3 N.A. 26.6 6.6 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.1 29.5
Protein Similarity: N.A. N.A. N.A. N.A. 40.3 44
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 20 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 20 14 0 7 7 40 0 0 7 0 7 40 14 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % C
% Asp: 0 0 7 0 7 0 0 0 0 0 0 0 7 0 0 % D
% Glu: 0 0 7 0 7 0 7 0 0 0 7 0 7 14 0 % E
% Phe: 0 0 7 7 0 7 7 0 0 0 0 0 0 7 0 % F
% Gly: 0 0 0 0 0 7 7 7 0 0 0 7 0 34 40 % G
% His: 7 0 0 0 0 0 0 7 7 0 0 0 0 0 0 % H
% Ile: 7 0 47 0 0 7 0 0 0 7 14 0 0 0 0 % I
% Lys: 7 0 0 0 0 0 0 0 14 14 0 7 0 0 7 % K
% Leu: 0 0 7 14 7 0 7 0 7 7 0 7 0 0 14 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 0 0 0 0 0 0 7 7 0 14 0 0 0 0 % N
% Pro: 54 0 7 47 20 54 7 7 0 0 0 40 20 7 7 % P
% Gln: 0 14 0 0 7 7 0 7 47 7 0 0 7 0 0 % Q
% Arg: 0 0 0 0 7 0 0 14 0 0 0 0 0 7 7 % R
% Ser: 7 67 0 14 0 0 7 7 14 47 54 14 14 7 7 % S
% Thr: 7 0 0 7 20 0 14 0 0 14 7 20 0 0 7 % T
% Val: 0 0 7 7 20 14 7 0 0 0 7 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 7 0 0 0 47 7 0 0 0 0 14 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _