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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SDR42E1 All Species: 10.91
Human Site: S359 Identified Species: 18.46
UniProt: Q8WUS8 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WUS8 NP_660151.2 393 44284 S359 A H G H G R S S G S R D S E C
Chimpanzee Pan troglodytes XP_001148161 393 44225 S359 A H G H G R S S G S R D S E C
Rhesus Macaque Macaca mulatta P27365 373 41987 W346 A Y K P L Y S W E E A K Q K T
Dog Lupus familis XP_546811 393 43999 S359 A H G H G R S S G N R D S E C
Cat Felis silvestris
Mouse Mus musculus Q9D665 394 43876 A360 A H G H G R G A A G Q D S E F
Rat Rattus norvegicus Q5PPL3 362 40393 G337 E K A K K L I G Y R P L V T M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508136 391 44010 L357 A Q G H G R K L K V C S L K D
Chicken Gallus gallus XP_414167 391 43627 P357 S Q G C G P K P R K Y T I T H
Frog Xenopus laevis Q0IH73 386 43592 D356 N H G Y G K Q D K K I K S N Y
Zebra Danio Brachydanio rerio A8DZE7 387 43577 R356 A R G H G K K R S R S S I R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781210 379 42410 S351 E R G H R K K S S S I G A F L
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001132313 479 53215 G380 R K R M E L D G P T I F T W L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FX01 439 48106 E370 A Q N Q P K T E V T E T I Q W
Baker's Yeast Sacchar. cerevisiae P53199 349 38688 K324 H N I A K A K K L L G Y T P R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 32.3 88.8 N.A. 79.4 29 N.A. 74.5 70.4 62 65.1 N.A. N.A. N.A. N.A. 44.2
Protein Similarity: 100 99.4 45.7 94.9 N.A. 88.3 46.8 N.A. 88 82.1 75.3 78.6 N.A. N.A. N.A. N.A. 59
P-Site Identity: 100 100 13.3 93.3 N.A. 60 0 N.A. 33.3 13.3 26.6 26.6 N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 100 26.6 100 N.A. 73.3 0 N.A. 40 20 40 33.3 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. 38.4 N.A. 30.5 28.7 N.A.
Protein Similarity: N.A. 51.3 N.A. 49.2 45.8 N.A.
P-Site Identity: N.A. 0 N.A. 6.6 0 N.A.
P-Site Similarity: N.A. 13.3 N.A. 33.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 58 0 8 8 0 8 0 8 8 0 8 0 8 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 22 % C
% Asp: 0 0 0 0 0 0 8 8 0 0 0 29 0 0 8 % D
% Glu: 15 0 0 0 8 0 0 8 8 8 8 0 0 29 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 8 % F
% Gly: 0 0 65 0 58 0 8 15 22 8 8 8 0 0 0 % G
% His: 8 36 0 50 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 8 0 0 0 8 0 0 0 22 0 22 0 0 % I
% Lys: 0 15 8 8 15 29 36 8 15 15 0 15 0 15 8 % K
% Leu: 0 0 0 0 8 15 0 8 8 8 0 8 8 0 15 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 8 8 8 0 0 0 0 0 0 8 0 0 0 8 0 % N
% Pro: 0 0 0 8 8 8 0 8 8 0 8 0 0 8 0 % P
% Gln: 0 22 0 8 0 0 8 0 0 0 8 0 8 8 0 % Q
% Arg: 8 15 8 0 8 36 0 8 8 15 22 0 0 8 8 % R
% Ser: 8 0 0 0 0 0 29 29 15 22 8 15 36 0 0 % S
% Thr: 0 0 0 0 0 0 8 0 0 15 0 15 15 15 8 % T
% Val: 0 0 0 0 0 0 0 0 8 8 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 8 % W
% Tyr: 0 8 0 8 0 8 0 0 8 0 8 8 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _