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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDR42E1
All Species:
31.21
Human Site:
Y142
Identified Species:
52.82
UniProt:
Q8WUS8
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUS8
NP_660151.2
393
44284
Y142
N
G
D
E
S
L
P
Y
L
P
L
H
L
H
P
Chimpanzee
Pan troglodytes
XP_001148161
393
44225
Y142
N
G
D
E
S
L
P
Y
L
P
L
H
L
H
P
Rhesus Macaque
Macaca mulatta
P27365
373
41987
E143
E
I
I
Q
N
G
H
E
E
E
P
L
E
N
T
Dog
Lupus familis
XP_546811
393
43999
Y142
N
G
D
E
S
L
P
Y
L
P
L
H
L
H
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D665
394
43876
Y143
N
G
D
E
S
L
P
Y
L
P
L
H
L
H
P
Rat
Rattus norvegicus
Q5PPL3
362
40393
A135
K
L
I
L
T
S
S
A
S
V
V
F
E
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508136
391
44010
Y140
N
G
D
E
S
L
P
Y
L
P
L
H
L
H
P
Chicken
Gallus gallus
XP_414167
391
43627
Y140
N
G
D
E
S
L
P
Y
L
P
L
H
L
H
P
Frog
Xenopus laevis
Q0IH73
386
43592
Y140
D
G
D
E
S
L
P
Y
L
P
Q
D
A
F
V
Zebra Danio
Brachydanio rerio
A8DZE7
387
43577
Y139
N
G
D
E
S
L
P
Y
L
P
L
H
L
H
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781210
379
42410
L140
N
G
D
E
T
L
P
L
L
P
L
S
A
H
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001132313
479
53215
F149
G
N
E
A
L
P
Y
F
P
I
E
D
H
V
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FX01
439
48106
L145
F
D
G
V
H
G
T
L
N
A
D
E
S
L
P
Baker's Yeast
Sacchar. cerevisiae
P53199
349
38688
T122
G
V
N
I
L
V
Y
T
S
S
A
G
V
I
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
32.3
88.8
N.A.
79.4
29
N.A.
74.5
70.4
62
65.1
N.A.
N.A.
N.A.
N.A.
44.2
Protein Similarity:
100
99.4
45.7
94.9
N.A.
88.3
46.8
N.A.
88
82.1
75.3
78.6
N.A.
N.A.
N.A.
N.A.
59
P-Site Identity:
100
100
0
100
N.A.
100
0
N.A.
100
100
60
100
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
100
100
20
100
N.A.
100
13.3
N.A.
100
100
66.6
100
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
38.4
N.A.
30.5
28.7
N.A.
Protein Similarity:
N.A.
51.3
N.A.
49.2
45.8
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
8
0
8
8
0
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
65
0
0
0
0
0
0
0
8
15
0
0
8
% D
% Glu:
8
0
8
65
0
0
0
8
8
8
8
8
15
0
0
% E
% Phe:
8
0
0
0
0
0
0
8
0
0
0
8
0
8
8
% F
% Gly:
15
65
8
0
0
15
0
0
0
0
0
8
0
8
0
% G
% His:
0
0
0
0
8
0
8
0
0
0
0
50
8
58
0
% H
% Ile:
0
8
15
8
0
0
0
0
0
8
0
0
0
8
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
8
0
8
15
65
0
15
65
0
58
8
50
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
58
8
8
0
8
0
0
0
8
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
8
65
0
8
65
8
0
0
0
58
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
58
8
8
0
15
8
0
8
8
0
0
% S
% Thr:
0
0
0
0
15
0
8
8
0
0
0
0
0
0
8
% T
% Val:
0
8
0
8
0
8
0
0
0
8
8
0
8
8
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
15
58
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _