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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM174
All Species:
8.79
Human Site:
S104
Identified Species:
24.17
UniProt:
Q8WUU8
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUU8
NP_694949.1
243
26287
S104
S
C
Q
L
C
K
E
S
E
E
R
V
P
D
S
Chimpanzee
Pan troglodytes
XP_517711
243
26194
S104
S
C
Q
L
C
K
E
S
E
E
R
V
P
D
S
Rhesus Macaque
Macaca mulatta
XP_001099857
243
26213
S104
S
C
Q
L
C
K
E
S
E
E
R
V
P
D
L
Dog
Lupus familis
XP_853225
304
32330
G168
S
C
Q
V
C
R
E
G
E
E
R
A
P
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCX7
243
26430
N104
S
C
Q
L
C
S
D
N
E
E
R
V
P
D
S
Rat
Rattus norvegicus
Q68FU0
243
26459
N104
S
C
Q
L
C
T
D
N
E
E
R
V
L
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508448
172
18111
A36
Q
V
S
D
D
D
K
A
G
A
T
L
L
F
S
Chicken
Gallus gallus
XP_001231595
243
26310
R104
T
C
K
P
C
K
E
R
E
E
N
M
L
D
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001344619
456
49253
I271
S
C
L
S
C
K
Q
I
E
E
E
I
T
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.4
57.2
N.A.
81.4
80.2
N.A.
51.8
58.4
N.A.
26.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.7
97.1
62.8
N.A.
87.6
87.6
N.A.
59.2
68.7
N.A.
36.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
66.6
N.A.
80
73.3
N.A.
6.6
46.6
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
93.3
86.6
N.A.
26.6
66.6
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
12
0
12
0
12
0
0
12
% A
% Cys:
0
89
0
0
89
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
12
12
23
0
0
0
0
0
0
78
0
% D
% Glu:
0
0
0
0
0
0
56
0
89
89
12
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
0
0
0
0
0
0
0
12
12
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
12
0
0
0
12
0
0
12
% I
% Lys:
0
0
12
0
0
56
12
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
12
56
0
0
0
0
0
0
0
12
34
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
23
0
0
12
0
0
0
0
% N
% Pro:
0
0
0
12
0
0
0
0
0
0
0
0
56
12
0
% P
% Gln:
12
0
67
0
0
0
12
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
12
0
12
0
0
67
0
0
0
0
% R
% Ser:
78
0
12
12
0
12
0
34
0
0
0
0
0
0
56
% S
% Thr:
12
0
0
0
0
12
0
0
0
0
12
0
12
0
0
% T
% Val:
0
12
0
12
0
0
0
0
0
0
0
56
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _