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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC38A5 All Species: 5.45
Human Site: S246 Identified Species: 13.33
UniProt: Q8WUX1 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WUX1 NP_277053.2 472 51457 S246 P S Q G L N S S C E A Q M F T
Chimpanzee Pan troglodytes XP_001138126 472 51458 S246 P S Q G L N S S C E A Q M F T
Rhesus Macaque Macaca mulatta XP_001102960 504 55810 L265 V V K E K V Q L Q I E P E A A
Dog Lupus familis XP_855349 709 77781 A421 P V G K V V V A A V I C L H N
Cat Felis silvestris
Mouse Mus musculus Q3U1J0 479 52598 A256 A F N S S C E A E L F T V D S
Rat Rattus norvegicus A2VCW5 479 52417 A256 A F N S S C E A K L F T V D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519161 498 55017 I259 L N S T H L M I N I S T P K A
Chicken Gallus gallus Q5F468 501 55512 T271 P F A D E N I T I S D A C K P
Frog Xenopus laevis Q6PF45 518 57172 I272 V A H F V I N I L V I A Y C L
Zebra Danio Brachydanio rerio Q5SPB1 504 55813 E271 Q T N N S T D E E C C K P K Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 58.7 27.6 N.A. 86.2 86.4 N.A. 65.2 48 20.6 46.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 71.8 38.9 N.A. 92.2 92.4 N.A. 77.1 64.8 38.4 62.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 6.6 N.A. 0 0 N.A. 0 13.3 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 6.6 26.6 N.A. 20 20 N.A. 13.3 20 20 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 10 10 0 0 0 0 30 10 0 20 20 0 10 20 % A
% Cys: 0 0 0 0 0 20 0 0 20 10 10 10 10 10 0 % C
% Asp: 0 0 0 10 0 0 10 0 0 0 10 0 0 20 0 % D
% Glu: 0 0 0 10 10 0 20 10 20 20 10 0 10 0 0 % E
% Phe: 0 30 0 10 0 0 0 0 0 0 20 0 0 20 0 % F
% Gly: 0 0 10 20 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 10 0 10 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 10 10 20 10 20 20 0 0 0 0 % I
% Lys: 0 0 10 10 10 0 0 0 10 0 0 10 0 30 0 % K
% Leu: 10 0 0 0 20 10 0 10 10 20 0 0 10 0 10 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 20 0 0 % M
% Asn: 0 10 30 10 0 30 10 0 10 0 0 0 0 0 10 % N
% Pro: 40 0 0 0 0 0 0 0 0 0 0 10 20 0 10 % P
% Gln: 10 0 20 0 0 0 10 0 10 0 0 20 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 20 10 20 30 0 20 20 0 10 10 0 0 0 20 % S
% Thr: 0 10 0 10 0 10 0 10 0 0 0 30 0 0 20 % T
% Val: 20 20 0 0 20 20 10 0 0 20 0 0 20 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _