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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHAC2 All Species: 44.24
Human Site: S138 Identified Species: 81.11
UniProt: Q8WUX2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WUX2 NP_001008708.1 184 20875 S138 I F N A A G P S G R N T E Y L
Chimpanzee Pan troglodytes XP_523053 222 24369 S172 I L A C R G F S G H N L E Y L
Rhesus Macaque Macaca mulatta XP_001099347 222 24360 S172 I L A C R G F S G H N L E Y L
Dog Lupus familis XP_854835 542 59041 S496 I F N A A G P S G R N T E Y L
Cat Felis silvestris
Mouse Mus musculus Q9CQG1 178 20134 S138 I F N A A G P S G R N T E Y L
Rat Rattus norvegicus Q641Z5 178 20148 S138 I F N A A G P S G R N T E Y L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516539 401 44696 S356 I F S A V G P S G K N T E Y L
Chicken Gallus gallus Q5ZI66 186 21075 S138 I I D A V G P S G R N T E Y L
Frog Xenopus laevis Q5PPV4 184 20983 S138 I L N A V G P S G R N T E Y L
Zebra Danio Brachydanio rerio Q4KMJ1 182 20744 S139 I V K S V G P S G K N T D Y L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122718 195 22242 S139 I L V S H G P S G A N T E Y L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781155 198 22643 S142 I V S S E G P S G K N K D Y L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32656 232 26275 S190 I A V S H G P S G S N Y E Y L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.8 42.3 32 N.A. 90.7 91.3 N.A. 35.9 78.4 85.3 69 N.A. N.A. 50.7 N.A. 54
Protein Similarity: 100 50.4 50.4 33.3 N.A. 94 94 N.A. 41.1 85.4 92.9 85.8 N.A. N.A. 67.1 N.A. 66.1
P-Site Identity: 100 53.3 53.3 100 N.A. 100 100 N.A. 80 80 86.6 60 N.A. N.A. 66.6 N.A. 53.3
P-Site Similarity: 100 53.3 53.3 100 N.A. 100 100 N.A. 93.3 86.6 86.6 80 N.A. N.A. 73.3 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 31.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 60 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 16 54 31 0 0 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 16 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 0 0 0 0 16 0 0 % D
% Glu: 0 0 0 0 8 0 0 0 0 0 0 0 85 0 0 % E
% Phe: 0 39 0 0 0 0 16 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 100 0 0 100 0 0 0 0 0 0 % G
% His: 0 0 0 0 16 0 0 0 0 16 0 0 0 0 0 % H
% Ile: 100 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 0 0 0 0 0 24 0 8 0 0 0 % K
% Leu: 0 31 0 0 0 0 0 0 0 0 0 16 0 0 100 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 39 0 0 0 0 0 0 0 100 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 85 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 16 0 0 0 0 47 0 0 0 0 0 % R
% Ser: 0 0 16 31 0 0 0 100 0 8 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 70 0 0 0 % T
% Val: 0 16 16 0 31 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 100 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _