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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHAC2 All Species: 13.64
Human Site: T101 Identified Species: 25
UniProt: Q8WUX2 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WUX2 NP_001008708.1 184 20875 T101 F Y P K D P T T K P F S V L L
Chimpanzee Pan troglodytes XP_523053 222 24369 A133 V T F Y P Q D A P D Q P L K A
Rhesus Macaque Macaca mulatta XP_001099347 222 24360 A133 V T F Y P Q D A P D Q P L K A
Dog Lupus familis XP_854835 542 59041 T459 F Y P K D P T T K P F S V L L
Cat Felis silvestris
Mouse Mus musculus Q9CQG1 178 20134 T101 F Y P K D S T T K P F S V L L
Rat Rattus norvegicus Q641Z5 178 20148 T101 F Y P K D S T T K P F S V L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516539 401 44696 V319 F Y P K D S A V K P F D V L L
Chicken Gallus gallus Q5ZI66 186 21075 I101 F Y P K D S S I K P F D V L L
Frog Xenopus laevis Q5PPV4 184 20983 I101 F Y P K D P S I Q P F N V L L
Zebra Danio Brachydanio rerio Q4KMJ1 182 20744 Q101 F H P K D E Q Q Q P M Q D T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122718 195 22242 S101 V L F Y P S Y S I K A F Y I T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781155 198 22643 K101 F Y P L Q S E K N S V Q E P F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32656 232 26275 R108 P E H A Q E V R E Y L N V R E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.8 42.3 32 N.A. 90.7 91.3 N.A. 35.9 78.4 85.3 69 N.A. N.A. 50.7 N.A. 54
Protein Similarity: 100 50.4 50.4 33.3 N.A. 94 94 N.A. 41.1 85.4 92.9 85.8 N.A. N.A. 67.1 N.A. 66.1
P-Site Identity: 100 0 0 100 N.A. 93.3 93.3 N.A. 73.3 73.3 73.3 40 N.A. N.A. 0 N.A. 20
P-Site Similarity: 100 6.6 6.6 100 N.A. 93.3 93.3 N.A. 73.3 80 93.3 53.3 N.A. N.A. 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 31.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 8 16 0 0 8 0 0 0 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 62 0 16 0 0 16 0 16 8 0 0 % D
% Glu: 0 8 0 0 0 16 8 0 8 0 0 0 8 0 8 % E
% Phe: 70 0 24 0 0 0 0 0 0 0 54 8 0 0 8 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 16 8 0 0 0 0 8 0 % I
% Lys: 0 0 0 62 0 0 0 8 47 8 0 0 0 16 0 % K
% Leu: 0 8 0 8 0 0 0 0 0 0 8 0 16 54 62 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 16 0 0 0 % N
% Pro: 8 0 70 0 24 24 0 0 16 62 0 16 0 8 0 % P
% Gln: 0 0 0 0 16 16 8 8 16 0 16 16 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % R
% Ser: 0 0 0 0 0 47 16 8 0 8 0 31 0 0 0 % S
% Thr: 0 16 0 0 0 0 31 31 0 0 0 0 0 8 8 % T
% Val: 24 0 0 0 0 0 8 8 0 0 8 0 62 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 62 0 24 0 0 8 0 0 8 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _