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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHMP7 All Species: 9.09
Human Site: S441 Identified Species: 22.22
UniProt: Q8WUX9 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WUX9 NP_689485.1 453 50911 S441 G L V P S S K S P K R Q L E P
Chimpanzee Pan troglodytes XP_001158823 453 50903 S441 G L V P S S K S P K R Q L E P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851170 540 59219 R425 G S G A R D S R S K G S A P P
Cat Felis silvestris
Mouse Mus musculus Q8R1T1 451 50614 S440 E G G L I P S S K S P K R Q L
Rat Rattus norvegicus NP_001102342 450 50525 P437 L S E G G L V P S S K S P K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506159 451 50327 S440 G G D L V P S S P S P K R F L
Chicken Gallus gallus Q5ZJB7 448 49761 S435 D L A Q K T P S A S S E P Q T
Frog Xenopus laevis Q7T0X5 422 47691 G410 A A H S P A D G S F L R S V P
Zebra Danio Brachydanio rerio Q6PBQ2 457 50962 S446 D K G L P R E S V S P Q R R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001195762 500 55993 G452 D L P E V P S G S P A E L D T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 76.6 N.A. 95.1 96 N.A. 89.8 75.2 45.4 52.2 N.A. N.A. N.A. N.A. 32
Protein Similarity: 100 99.5 N.A. 78.3 N.A. 96.6 97.1 N.A. 92.4 85.2 66.2 72.4 N.A. N.A. N.A. N.A. 53.6
P-Site Identity: 100 100 N.A. 20 N.A. 6.6 0 N.A. 20 13.3 6.6 13.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 N.A. 20 N.A. 20 13.3 N.A. 26.6 33.3 20 20 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 10 0 10 0 0 10 0 10 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 30 0 10 0 0 10 10 0 0 0 0 0 0 10 0 % D
% Glu: 10 0 10 10 0 0 10 0 0 0 0 20 0 20 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % F
% Gly: 40 20 30 10 10 0 0 20 0 0 10 0 0 0 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 10 0 20 0 10 30 10 20 0 10 0 % K
% Leu: 10 40 0 30 0 10 0 0 0 0 10 0 30 0 30 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 20 20 30 10 10 30 10 30 0 20 10 40 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 30 0 20 0 % Q
% Arg: 0 0 0 0 10 10 0 10 0 0 20 10 30 10 10 % R
% Ser: 0 20 0 10 20 20 40 60 40 50 10 20 10 0 0 % S
% Thr: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 20 % T
% Val: 0 0 20 0 20 0 10 0 10 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _