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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEPDC1B
All Species:
10.91
Human Site:
S445
Identified Species:
26.67
UniProt:
Q8WUY9
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUY9
NP_001138680.1
529
61771
S445
E
E
F
E
Y
Q
R
S
Y
G
S
Q
E
P
L
Chimpanzee
Pan troglodytes
XP_517749
529
61843
S445
E
E
F
E
Y
Q
R
S
Y
G
S
Q
E
P
L
Rhesus Macaque
Macaca mulatta
XP_001103700
529
61874
S445
E
E
F
E
Y
Q
R
S
Y
G
S
Q
E
P
L
Dog
Lupus familis
XP_851234
541
63392
A457
E
E
F
E
Y
Q
R
A
Y
G
S
Q
E
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH88
529
61890
A445
E
E
F
E
Y
Q
R
A
Y
G
S
Q
E
P
L
Rat
Rattus norvegicus
Q4QR86
511
58183
G438
K
L
L
A
I
Q
K
G
R
D
P
N
K
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512859
866
98552
I789
R
E
F
D
E
Q
K
I
S
T
S
Q
A
A
I
Chicken
Gallus gallus
Q5ZLD2
529
61095
A445
D
E
F
E
Y
Q
R
A
T
G
S
Q
E
P
L
Frog
Xenopus laevis
Q6ING4
806
92590
L729
Q
E
F
E
E
Q
R
L
A
T
S
Q
A
A
I
Zebra Danio
Brachydanio rerio
Q803Q4
800
90672
S725
E
Q
Q
K
L
S
V
S
Q
S
A
L
A
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.6
91.8
N.A.
93.9
22.8
N.A.
32.5
75.4
35.1
33.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
99.2
94
N.A.
96.9
43.8
N.A.
44.6
86.7
49.3
47.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
6.6
N.A.
33.3
80
46.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
53.3
93.3
60
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
30
10
0
10
0
30
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
0
0
0
0
10
0
0
0
20
0
% D
% Glu:
60
80
0
70
20
0
0
0
0
0
0
0
60
0
0
% E
% Phe:
0
0
80
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
60
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
20
% I
% Lys:
10
0
0
10
0
0
20
0
0
0
0
0
10
0
0
% K
% Leu:
0
10
10
0
10
0
0
10
0
0
0
10
0
0
70
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
0
60
0
% P
% Gln:
10
10
10
0
0
90
0
0
10
0
0
80
0
0
0
% Q
% Arg:
10
0
0
0
0
0
70
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
0
40
10
10
80
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
20
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
60
0
0
0
50
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _