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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCAF4
All Species:
7.88
Human Site:
S43
Identified Species:
19.26
UniProt:
Q8WV16
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WV16
NP_056419.2
495
55694
S43
A
A
Q
P
A
H
D
S
G
H
G
D
D
E
S
Chimpanzee
Pan troglodytes
XP_001147813
495
55693
S43
A
A
Q
P
A
H
D
S
S
H
G
D
D
E
S
Rhesus Macaque
Macaca mulatta
XP_001085856
495
55520
S43
A
A
R
S
A
Q
D
S
S
H
G
D
D
E
S
Dog
Lupus familis
XP_547889
530
58560
G77
E
Q
S
P
Q
D
S
G
P
I
S
D
D
E
S
Cat
Felis silvestris
Mouse
Mus musculus
NP_084522
519
58098
G43
S
Q
S
S
Q
D
S
G
H
H
D
A
E
S
P
Rat
Rattus norvegicus
NP_001102186
518
57947
G43
S
Q
S
S
Q
D
S
G
H
H
D
V
E
C
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421173
500
56103
N48
E
E
A
Q
S
P
V
N
P
V
P
S
C
S
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956995
505
56840
A44
S
D
R
T
A
S
D
A
G
S
S
S
A
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785369
524
58817
G50
S
P
T
T
S
E
A
G
S
L
T
R
N
H
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001144864
497
53974
R53
C
S
R
K
R
A
R
R
P
E
L
L
N
A
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.7
79.6
N.A.
77
77.9
N.A.
N.A.
65.5
N.A.
58
N.A.
N.A.
N.A.
N.A.
23.2
Protein Similarity:
100
99.3
98.3
86
N.A.
85.9
86
N.A.
N.A.
79
N.A.
74.4
N.A.
N.A.
N.A.
N.A.
41.2
P-Site Identity:
100
93.3
73.3
33.3
N.A.
6.6
6.6
N.A.
N.A.
0
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
80
33.3
N.A.
20
20
N.A.
N.A.
13.3
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
20.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
37.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
30
10
0
40
10
10
10
0
0
0
10
10
10
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% C
% Asp:
0
10
0
0
0
30
40
0
0
0
20
40
40
0
0
% D
% Glu:
20
10
0
0
0
10
0
0
0
10
0
0
20
40
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
40
20
0
30
0
0
0
10
% G
% His:
0
0
0
0
0
20
0
0
20
50
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
10
10
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
20
0
0
% N
% Pro:
0
10
0
30
0
10
0
0
30
0
10
0
0
0
20
% P
% Gln:
0
30
20
10
30
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
30
0
10
0
10
10
0
0
0
10
0
0
10
% R
% Ser:
40
10
30
30
20
10
30
30
30
10
20
20
0
30
60
% S
% Thr:
0
0
10
20
0
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _