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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCAF4
All Species:
27.13
Human Site:
Y490
Identified Species:
66.32
UniProt:
Q8WV16
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WV16
NP_056419.2
495
55694
Y490
M
A
V
G
Q
D
L
Y
C
Y
S
Y
S
_
_
Chimpanzee
Pan troglodytes
XP_001147813
495
55693
Y490
M
A
V
G
Q
D
L
Y
C
Y
S
Y
S
_
_
Rhesus Macaque
Macaca mulatta
XP_001085856
495
55520
Y490
M
A
V
G
Q
D
L
Y
C
Y
S
Y
S
_
_
Dog
Lupus familis
XP_547889
530
58560
Y525
M
A
V
Q
Q
D
L
Y
C
F
S
Y
T
_
_
Cat
Felis silvestris
Mouse
Mus musculus
NP_084522
519
58098
Y491
M
A
V
Q
Q
D
L
Y
C
F
A
Y
S
S
S
Rat
Rattus norvegicus
NP_001102186
518
57947
Y490
M
A
V
Q
Q
D
L
Y
C
F
P
Y
S
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421173
500
56103
Y495
M
A
V
K
Q
D
L
Y
H
F
S
Y
N
_
_
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956995
505
56840
Y487
M
A
V
R
H
D
L
Y
Y
Y
S
Y
N
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785369
524
58817
W510
G
Q
E
R
Q
I
H
W
Y
P
M
R
T
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001144864
497
53974
R488
W
G
A
W
L
G
S
R
A
G
L
F
Y
M
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.7
79.6
N.A.
77
77.9
N.A.
N.A.
65.5
N.A.
58
N.A.
N.A.
N.A.
N.A.
23.2
Protein Similarity:
100
99.3
98.3
86
N.A.
85.9
86
N.A.
N.A.
79
N.A.
74.4
N.A.
N.A.
N.A.
N.A.
41.2
P-Site Identity:
100
100
100
76.9
N.A.
66.6
66.6
N.A.
N.A.
69.2
N.A.
60
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
92.3
N.A.
80
73.3
N.A.
N.A.
84.6
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
20.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
37.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
80
10
0
0
0
0
0
10
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
60
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
80
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
40
0
10
0
0
0
% F
% Gly:
10
10
0
30
0
10
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
10
0
10
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
0
10
0
80
0
0
0
10
0
0
0
0
% L
% Met:
80
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% P
% Gln:
0
10
0
30
80
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
20
0
0
0
10
0
0
0
10
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
0
0
0
60
0
50
20
20
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% T
% Val:
0
0
80
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
10
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
20
40
0
80
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
50
% _