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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NSMCE1
All Species:
23.94
Human Site:
Y219
Identified Species:
65.83
UniProt:
Q8WV22
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WV22
NP_659547.2
266
30855
Y219
H
L
P
C
V
A
K
Y
F
Q
S
N
A
E
P
Chimpanzee
Pan troglodytes
XP_510891
265
30780
Y218
H
L
P
C
V
A
K
Y
F
Q
S
N
A
E
P
Rhesus Macaque
Macaca mulatta
XP_001100952
266
30894
Y219
H
L
P
C
V
A
K
Y
F
Q
S
N
T
E
P
Dog
Lupus familis
XP_536928
283
32803
Y236
H
L
P
C
V
A
K
Y
F
Q
S
N
S
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D720
266
30690
Y219
H
L
P
C
V
A
K
Y
F
Q
S
I
P
E
P
Rat
Rattus norvegicus
Q499U6
266
30684
Y219
H
L
P
C
V
A
K
Y
F
Q
S
T
A
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414884
256
29520
A197
S
L
A
I
Q
S
Q
A
C
E
T
C
G
T
G
Frog
Xenopus laevis
Q6PAF4
270
30929
Y213
H
L
Q
C
A
G
K
Y
F
H
G
K
A
N
P
Zebra Danio
Brachydanio rerio
Q6DGT7
239
27187
H194
F
R
A
R
S
D
P
H
C
P
A
C
N
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97.3
85.5
N.A.
89.4
91.7
N.A.
N.A.
54.1
49.6
41.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
98.8
90.8
N.A.
96.9
98.1
N.A.
N.A.
73.3
67
63.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
93.3
N.A.
N.A.
6.6
53.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
86.6
93.3
N.A.
N.A.
33.3
53.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
23
0
12
67
0
12
0
0
12
0
45
0
0
% A
% Cys:
0
0
0
78
0
0
0
0
23
0
0
23
0
0
0
% C
% Asp:
0
0
0
0
0
12
0
0
0
0
0
0
0
12
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
12
0
0
0
67
0
% E
% Phe:
12
0
0
0
0
0
0
0
78
0
0
0
0
0
12
% F
% Gly:
0
0
0
0
0
12
0
0
0
0
12
0
12
0
12
% G
% His:
78
0
0
0
0
0
0
12
0
12
0
0
0
0
0
% H
% Ile:
0
0
0
12
0
0
0
0
0
0
0
12
0
0
0
% I
% Lys:
0
0
0
0
0
0
78
0
0
0
0
12
0
0
0
% K
% Leu:
0
89
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
45
12
12
0
% N
% Pro:
0
0
67
0
0
0
12
0
0
12
0
0
12
0
78
% P
% Gln:
0
0
12
0
12
0
12
0
0
67
0
0
0
0
0
% Q
% Arg:
0
12
0
12
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
0
0
12
12
0
0
0
0
67
0
12
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
12
12
12
12
0
% T
% Val:
0
0
0
0
67
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
78
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _