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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUDT8
All Species:
6.06
Human Site:
S128
Identified Species:
12.12
UniProt:
Q8WV74
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WV74
NP_862826.1
236
25370
S128
V
G
P
L
D
P
Q
S
L
R
P
N
S
E
E
Chimpanzee
Pan troglodytes
XP_522294
236
25352
S128
V
G
P
L
D
P
Q
S
L
R
P
N
S
E
E
Rhesus Macaque
Macaca mulatta
XP_001117890
203
22156
P98
L
D
P
Q
S
L
R
P
N
S
E
E
V
D
E
Dog
Lupus familis
XP_851711
210
23034
P105
H
V
W
G
V
L
Q
P
V
H
D
R
Q
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR24
210
23234
P105
H
V
W
G
V
L
Q
P
V
Y
D
R
E
K
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070784
293
32577
P185
E
V
W
G
V
L
K
P
L
R
D
K
S
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572927
283
32003
P175
V
P
V
V
G
V
V
P
D
F
S
L
S
E
L
Honey Bee
Apis mellifera
XP_001121306
246
28506
I134
L
K
I
P
K
K
K
I
D
I
W
T
S
G
N
Nematode Worm
Caenorhab. elegans
Q23236
188
21299
T83
R
Q
A
D
F
N
V
T
P
I
V
G
Y
I
S
Sea Urchin
Strong. purpuratus
XP_785895
226
24855
R121
L
A
P
V
G
R
E
R
I
T
V
V
P
I
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LET2
222
25661
M117
P
F
V
N
K
K
G
M
S
V
A
P
V
I
G
Baker's Yeast
Sacchar. cerevisiae
Q12524
340
39736
S132
Y
L
S
R
T
F
L
S
V
K
P
M
V
C
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
73.7
79.2
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
39.2
N.A.
30.7
38.2
29.6
41.9
Protein Similarity:
100
100
76.6
82.6
N.A.
80.5
N.A.
N.A.
N.A.
N.A.
N.A.
50.8
N.A.
44.1
52
42.7
56.7
P-Site Identity:
100
100
13.3
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
20
6.6
0
6.6
P-Site Similarity:
100
100
33.3
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
26.6
20
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.5
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.5
36.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
0
0
0
0
0
0
9
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
9
0
9
17
0
0
0
17
0
25
0
0
9
0
% D
% Glu:
9
0
0
0
0
0
9
0
0
0
9
9
9
25
25
% E
% Phe:
0
9
0
0
9
9
0
0
0
9
0
0
0
0
9
% F
% Gly:
0
17
0
25
17
0
9
0
0
0
0
9
0
17
9
% G
% His:
17
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
9
9
17
0
0
0
25
9
% I
% Lys:
0
9
0
0
17
17
17
0
0
9
0
9
0
17
0
% K
% Leu:
25
9
0
17
0
34
9
0
25
0
0
9
0
0
9
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
9
% M
% Asn:
0
0
0
9
0
9
0
0
9
0
0
17
0
0
9
% N
% Pro:
9
9
34
9
0
17
0
42
9
0
25
9
9
0
0
% P
% Gln:
0
9
0
9
0
0
34
0
0
0
0
0
9
0
0
% Q
% Arg:
9
0
0
9
0
9
9
9
0
25
0
17
0
0
0
% R
% Ser:
0
0
9
0
9
0
0
25
9
9
9
0
42
0
9
% S
% Thr:
0
0
0
0
9
0
0
9
0
9
0
9
0
0
0
% T
% Val:
25
25
17
17
25
9
17
0
25
9
17
9
25
0
0
% V
% Trp:
0
0
25
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _