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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUDT8
All Species:
6.36
Human Site:
S227
Identified Species:
12.73
UniProt:
Q8WV74
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WV74
NP_862826.1
236
25370
S227
L
A
S
P
C
Q
A
S
S
T
P
G
L
N
K
Chimpanzee
Pan troglodytes
XP_522294
236
25352
S227
L
A
S
P
C
Q
A
S
S
T
P
G
L
N
K
Rhesus Macaque
Macaca mulatta
XP_001117890
203
22156
S195
V
S
P
C
Q
A
S
S
T
S
G
L
N
K
G
Dog
Lupus familis
XP_851711
210
23034
L202
P
G
A
Y
Q
P
C
L
A
T
S
K
R
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR24
210
23234
L202
P
G
F
Y
Q
P
S
L
A
V
P
E
L
P
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070784
293
32577
R283
P
E
Q
M
L
E
R
R
V
I
Q
Q
Q
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572927
283
32003
H274
K
L
P
H
H
R
E
H
S
A
G
D
P
S
M
Honey Bee
Apis mellifera
XP_001121306
246
28506
L237
Y
K
L
E
F
I
S
L
P
K
I
L
P
Q
K
Nematode Worm
Caenorhab. elegans
Q23236
188
21299
K180
L
L
N
P
D
V
Y
K
H
D
L
I
V
K
F
Sea Urchin
Strong. purpuratus
XP_785895
226
24855
V218
Y
R
S
L
L
S
Q
V
K
K
E
Q
A
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LET2
222
25661
K214
L
P
E
F
Q
E
R
K
P
S
F
W
N
Q
P
Baker's Yeast
Sacchar. cerevisiae
Q12524
340
39736
L265
W
G
L
T
C
K
I
L
F
D
V
S
C
I
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
73.7
79.2
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
39.2
N.A.
30.7
38.2
29.6
41.9
Protein Similarity:
100
100
76.6
82.6
N.A.
80.5
N.A.
N.A.
N.A.
N.A.
N.A.
50.8
N.A.
44.1
52
42.7
56.7
P-Site Identity:
100
100
6.6
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
6.6
6.6
13.3
6.6
P-Site Similarity:
100
100
40
20
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
20
13.3
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.5
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.5
36.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
9
0
0
9
17
0
17
9
0
0
9
9
9
% A
% Cys:
0
0
0
9
25
0
9
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
0
17
0
9
0
0
0
% D
% Glu:
0
9
9
9
0
17
9
0
0
0
9
9
0
0
0
% E
% Phe:
0
0
9
9
9
0
0
0
9
0
9
0
0
0
9
% F
% Gly:
0
25
0
0
0
0
0
0
0
0
17
17
0
0
9
% G
% His:
0
0
0
9
9
0
0
9
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
9
0
0
9
9
9
0
9
0
% I
% Lys:
9
9
0
0
0
9
0
17
9
17
0
9
0
17
25
% K
% Leu:
34
17
17
9
17
0
0
34
0
0
9
17
25
9
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
17
17
0
% N
% Pro:
25
9
17
25
0
17
0
0
17
0
25
0
17
9
9
% P
% Gln:
0
0
9
0
34
17
9
0
0
0
9
17
9
25
0
% Q
% Arg:
0
9
0
0
0
9
17
9
0
0
0
0
9
0
17
% R
% Ser:
0
9
25
0
0
9
25
25
25
17
9
9
0
9
9
% S
% Thr:
0
0
0
9
0
0
0
0
9
25
0
0
0
0
9
% T
% Val:
9
0
0
0
0
9
0
9
9
9
9
0
9
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
17
0
0
17
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _