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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUDT8 All Species: 13.33
Human Site: S65 Identified Species: 26.67
UniProt: Q8WV74 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WV74 NP_862826.1 236 25370 S65 G R H K G D V S F P G G K C D
Chimpanzee Pan troglodytes XP_522294 236 25352 S65 G R H K G D V S F P G G K C D
Rhesus Macaque Macaca mulatta XP_001117890 203 22156 D42 G G K C D P A D Q D V V H T A
Dog Lupus familis XP_851711 210 23034 Y49 R G V P A L L Y T L R S S R L
Cat Felis silvestris
Mouse Mus musculus Q9CR24 210 23234 Y49 R G V P A L L Y T L R S S R L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001070784 293 32577 A112 E R D T H R W A A V L V C L C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572927 283 32003 S118 R S H S F Q I S F P G G R R D
Honey Bee Apis mellifera XP_001121306 246 28506 A71 D H N T T Q A A V L I P L C T
Nematode Worm Caenorhab. elegans Q23236 188 21299 S27 K R S I H L R S H R G E V C F
Sea Urchin Strong. purpuratus XP_785895 226 24855 T65 C I L F T L R T R T L K D H S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LET2 222 25661 T61 I L T K R S T T L S S H P G E
Baker's Yeast Sacchar. cerevisiae Q12524 340 39736 S73 R S F S G D V S F P G G K A D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 100 73.7 79.2 N.A. 73.3 N.A. N.A. N.A. N.A. N.A. 39.2 N.A. 30.7 38.2 29.6 41.9
Protein Similarity: 100 100 76.6 82.6 N.A. 80.5 N.A. N.A. N.A. N.A. N.A. 50.8 N.A. 44.1 52 42.7 56.7
P-Site Identity: 100 100 6.6 0 N.A. 0 N.A. N.A. N.A. N.A. N.A. 6.6 N.A. 46.6 6.6 26.6 0
P-Site Similarity: 100 100 6.6 6.6 N.A. 6.6 N.A. N.A. N.A. N.A. N.A. 13.3 N.A. 60 20 26.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. 27.5 22.3 N.A.
Protein Similarity: N.A. N.A. N.A. 41.5 36.1 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 66.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 17 0 17 17 9 0 0 0 0 9 9 % A
% Cys: 9 0 0 9 0 0 0 0 0 0 0 0 9 34 9 % C
% Asp: 9 0 9 0 9 25 0 9 0 9 0 0 9 0 34 % D
% Glu: 9 0 0 0 0 0 0 0 0 0 0 9 0 0 9 % E
% Phe: 0 0 9 9 9 0 0 0 34 0 0 0 0 0 9 % F
% Gly: 25 25 0 0 25 0 0 0 0 0 42 34 0 9 0 % G
% His: 0 9 25 0 17 0 0 0 9 0 0 9 9 9 0 % H
% Ile: 9 9 0 9 0 0 9 0 0 0 9 0 0 0 0 % I
% Lys: 9 0 9 25 0 0 0 0 0 0 0 9 25 0 0 % K
% Leu: 0 9 9 0 0 34 17 0 9 25 17 0 9 9 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 17 0 9 0 0 0 34 0 9 9 0 0 % P
% Gln: 0 0 0 0 0 17 0 0 9 0 0 0 0 0 0 % Q
% Arg: 34 34 0 0 9 9 17 0 9 9 17 0 9 25 0 % R
% Ser: 0 17 9 17 0 9 0 42 0 9 9 17 17 0 9 % S
% Thr: 0 0 9 17 17 0 9 17 17 9 0 0 0 9 9 % T
% Val: 0 0 17 0 0 0 25 0 9 9 9 17 9 0 0 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _