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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUDT8
All Species:
5.45
Human Site:
T22
Identified Species:
10.91
UniProt:
Q8WV74
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WV74
NP_862826.1
236
25370
T22
R
R
L
L
A
G
A
T
A
R
L
R
A
R
P
Chimpanzee
Pan troglodytes
XP_522294
236
25352
T22
R
R
L
L
A
G
A
T
A
R
L
R
A
R
P
Rhesus Macaque
Macaca mulatta
XP_001117890
203
22156
Dog
Lupus familis
XP_851711
210
23034
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR24
210
23234
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070784
293
32577
A69
E
S
R
P
A
V
F
A
I
Q
R
R
R
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572927
283
32003
T75
F
P
R
P
K
A
L
T
P
S
R
R
E
K
Q
Honey Bee
Apis mellifera
XP_001121306
246
28506
F28
R
N
I
N
A
I
K
F
E
H
L
R
P
E
V
Nematode Worm
Caenorhab. elegans
Q23236
188
21299
Sea Urchin
Strong. purpuratus
XP_785895
226
24855
M22
V
E
N
K
E
R
V
M
S
S
L
S
S
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LET2
222
25661
F18
L
Q
N
L
I
K
L
F
Q
N
C
Q
T
H
P
Baker's Yeast
Sacchar. cerevisiae
Q12524
340
39736
R30
F
H
K
T
P
Y
T
R
S
S
I
W
P
F
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
73.7
79.2
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
39.2
N.A.
30.7
38.2
29.6
41.9
Protein Similarity:
100
100
76.6
82.6
N.A.
80.5
N.A.
N.A.
N.A.
N.A.
N.A.
50.8
N.A.
44.1
52
42.7
56.7
P-Site Identity:
100
100
0
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
13.3
26.6
0
6.6
P-Site Similarity:
100
100
0
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
20
33.3
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.5
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.5
36.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
34
9
17
9
17
0
0
0
17
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
9
0
0
9
0
0
0
9
0
0
0
9
9
0
% E
% Phe:
17
0
0
0
0
0
9
17
0
0
0
0
0
9
0
% F
% Gly:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% G
% His:
0
9
0
0
0
0
0
0
0
9
0
0
0
9
9
% H
% Ile:
0
0
9
0
9
9
0
0
9
0
9
0
0
0
0
% I
% Lys:
0
0
9
9
9
9
9
0
0
0
0
0
0
17
9
% K
% Leu:
9
0
17
25
0
0
17
0
0
0
34
0
0
9
9
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
9
17
9
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
9
0
17
9
0
0
0
9
0
0
0
17
0
25
% P
% Gln:
0
9
0
0
0
0
0
0
9
9
0
9
0
0
9
% Q
% Arg:
25
17
17
0
0
9
0
9
0
17
17
42
9
17
0
% R
% Ser:
0
9
0
0
0
0
0
0
17
25
0
9
9
0
0
% S
% Thr:
0
0
0
9
0
0
9
25
0
0
0
0
9
0
0
% T
% Val:
9
0
0
0
0
9
9
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _