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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUDT8
All Species:
6.36
Human Site:
Y166
Identified Species:
12.73
UniProt:
Q8WV74
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WV74
NP_862826.1
236
25370
Y166
C
R
G
G
H
F
R
Y
T
L
P
V
F
L
H
Chimpanzee
Pan troglodytes
XP_522294
236
25352
Y166
C
R
G
G
H
F
R
Y
T
L
P
V
F
L
H
Rhesus Macaque
Macaca mulatta
XP_001117890
203
22156
T134
Q
R
G
H
F
R
Y
T
L
P
V
F
L
H
G
Dog
Lupus familis
XP_851711
210
23034
A141
K
E
V
D
Q
V
F
A
L
P
L
A
H
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR24
210
23234
E141
E
E
V
D
E
V
F
E
M
S
L
A
H
L
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070784
293
32577
L222
E
V
V
E
I
F
T
L
T
L
E
H
L
C
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572927
283
32003
S213
T
R
H
T
Q
F
R
S
G
Y
S
G
P
V
F
Honey Bee
Apis mellifera
XP_001121306
246
28506
F176
T
D
E
V
E
E
A
F
F
F
S
L
R
N
L
Nematode Worm
Caenorhab. elegans
Q23236
188
21299
K119
P
I
D
E
L
I
K
K
A
G
L
T
K
F
Q
Sea Urchin
Strong. purpuratus
XP_785895
226
24855
L157
F
V
M
T
L
S
H
L
C
R
P
A
C
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LET2
222
25661
L153
D
V
P
L
E
M
F
L
K
D
R
N
R
R
A
Baker's Yeast
Sacchar. cerevisiae
Q12524
340
39736
K204
Q
A
E
Y
F
E
R
K
E
Y
K
L
N
W
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
73.7
79.2
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
39.2
N.A.
30.7
38.2
29.6
41.9
Protein Similarity:
100
100
76.6
82.6
N.A.
80.5
N.A.
N.A.
N.A.
N.A.
N.A.
50.8
N.A.
44.1
52
42.7
56.7
P-Site Identity:
100
100
13.3
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
20
0
0
6.6
P-Site Similarity:
100
100
13.3
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
26.6
13.3
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.5
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.5
36.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
9
9
9
0
0
25
0
0
17
% A
% Cys:
17
0
0
0
0
0
0
0
9
0
0
0
9
9
0
% C
% Asp:
9
9
9
17
0
0
0
0
0
9
0
0
0
0
0
% D
% Glu:
17
17
17
17
25
17
0
9
9
0
9
0
0
0
9
% E
% Phe:
9
0
0
0
17
34
25
9
9
9
0
9
17
9
9
% F
% Gly:
0
0
25
17
0
0
0
0
9
9
0
9
0
0
17
% G
% His:
0
0
9
9
17
0
9
0
0
0
0
9
17
9
17
% H
% Ile:
0
9
0
0
9
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
0
0
0
0
9
17
9
0
9
0
9
0
0
% K
% Leu:
0
0
0
9
17
0
0
25
17
25
25
17
17
34
25
% L
% Met:
0
0
9
0
0
9
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
9
9
9
0
% N
% Pro:
9
0
9
0
0
0
0
0
0
17
25
0
9
0
0
% P
% Gln:
17
0
0
0
17
0
0
0
0
0
0
0
0
9
9
% Q
% Arg:
0
34
0
0
0
9
34
0
0
9
9
0
17
9
0
% R
% Ser:
0
0
0
0
0
9
0
9
0
9
17
0
0
0
0
% S
% Thr:
17
0
0
17
0
0
9
9
25
0
0
9
0
0
0
% T
% Val:
0
25
25
9
0
17
0
0
0
0
9
17
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
9
0
0
9
17
0
17
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _