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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MITD1
All Species:
28.79
Human Site:
S176
Identified Species:
52.78
UniProt:
Q8WV92
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WV92
NP_620153.1
249
29314
S176
G
L
Q
E
I
E
E
S
L
R
S
H
G
V
L
Chimpanzee
Pan troglodytes
XP_515647
249
29297
S176
G
L
Q
E
I
E
E
S
L
R
S
H
G
V
L
Rhesus Macaque
Macaca mulatta
XP_001103841
249
29183
S176
G
L
Q
E
I
E
E
S
L
R
S
H
G
V
L
Dog
Lupus familis
XP_531787
249
29178
S176
G
L
Q
E
I
K
K
S
L
Q
D
H
G
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDV8
249
28828
S176
G
L
E
E
I
K
Q
S
L
G
S
H
G
V
V
Rat
Rattus norvegicus
Q5I0J5
249
28830
S176
G
L
E
E
I
K
Q
S
L
R
S
H
G
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416894
250
29047
S177
G
L
E
E
I
K
Q
S
L
R
N
H
G
I
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956495
190
22412
L125
L
L
S
K
D
I
C
L
D
I
Q
Y
S
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647846
241
27913
T176
D
L
E
R
R
N
V
T
V
Y
I
K
Y
E
D
Honey Bee
Apis mellifera
XP_001120882
245
28077
S178
I
S
F
E
F
K
F
S
D
T
L
H
D
R
Q
Nematode Worm
Caenorhab. elegans
NP_499492
235
26759
R170
L
S
K
S
L
A
K
R
G
V
M
F
N
V
E
Sea Urchin
Strong. purpuratus
XP_794045
238
27442
E173
S
L
A
E
H
S
V
E
M
I
V
S
Y
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P52917
437
48154
A285
I
P
W
Q
L
D
S
A
I
R
R
R
F
E
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.1
83.5
N.A.
84.7
85.5
N.A.
N.A.
71.1
N.A.
51.4
N.A.
33.7
48.1
34.1
51.4
Protein Similarity:
100
100
99.1
91.5
N.A.
90.3
90.3
N.A.
N.A.
84.8
N.A.
63.8
N.A.
53.4
67
57
70.6
P-Site Identity:
100
100
100
73.3
N.A.
66.6
73.3
N.A.
N.A.
60
N.A.
6.6
N.A.
6.6
20
6.6
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
100
N.A.
N.A.
93.3
N.A.
20
N.A.
26.6
26.6
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
8
0
0
16
0
8
0
8
0
16
% D
% Glu:
0
0
31
70
0
24
24
8
0
0
0
0
0
16
8
% E
% Phe:
0
0
8
0
8
0
8
0
0
0
0
8
8
0
0
% F
% Gly:
54
0
0
0
0
0
0
0
8
8
0
0
54
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
62
0
0
0
% H
% Ile:
16
0
0
0
54
8
0
0
8
16
8
0
0
8
0
% I
% Lys:
0
0
8
8
0
39
16
0
0
0
0
8
0
0
0
% K
% Leu:
16
77
0
0
16
0
0
8
54
0
8
0
0
0
31
% L
% Met:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
8
0
8
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
31
8
0
0
24
0
0
8
8
0
0
0
8
% Q
% Arg:
0
0
0
8
8
0
0
8
0
47
8
8
0
8
8
% R
% Ser:
8
16
8
8
0
8
8
62
0
0
39
8
8
16
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
16
% T
% Val:
0
0
0
0
0
0
16
0
8
8
8
0
0
54
16
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
8
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _