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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MITD1
All Species:
25.45
Human Site:
Y225
Identified Species:
46.67
UniProt:
Q8WV92
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WV92
NP_620153.1
249
29314
Y225
Q
S
R
F
S
L
G
Y
C
D
F
D
L
R
P
Chimpanzee
Pan troglodytes
XP_515647
249
29297
Y225
Q
S
R
F
S
L
G
Y
C
D
F
D
L
R
P
Rhesus Macaque
Macaca mulatta
XP_001103841
249
29183
Y225
Q
S
R
F
S
L
G
Y
C
D
F
D
L
R
P
Dog
Lupus familis
XP_531787
249
29178
Y225
Q
S
R
F
S
L
G
Y
C
D
F
D
L
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDV8
249
28828
Y225
Q
G
R
F
S
L
G
Y
Y
D
L
D
L
R
P
Rat
Rattus norvegicus
Q5I0J5
249
28830
Y225
Q
G
R
F
S
L
G
Y
C
D
L
D
L
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416894
250
29047
Y226
Q
G
R
F
S
I
G
Y
C
D
F
D
L
R
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956495
190
22412
C167
G
R
F
S
V
G
Y
C
D
Y
D
L
R
E
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647846
241
27913
L218
N
P
M
Y
S
I
G
L
V
N
Y
K
F
R
K
Honey Bee
Apis mellifera
XP_001120882
245
28077
C222
C
D
L
E
L
R
P
C
S
E
T
T
I
D
I
Nematode Worm
Caenorhab. elegans
NP_499492
235
26759
V212
K
A
S
D
G
K
Y
V
L
G
A
N
D
M
D
Sea Urchin
Strong. purpuratus
XP_794045
238
27442
C215
G
Q
Y
S
I
G
F
C
D
M
D
L
R
R
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P52917
437
48154
D405
E
P
D
L
T
I
K
D
F
L
K
A
I
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.1
83.5
N.A.
84.7
85.5
N.A.
N.A.
71.1
N.A.
51.4
N.A.
33.7
48.1
34.1
51.4
Protein Similarity:
100
100
99.1
91.5
N.A.
90.3
90.3
N.A.
N.A.
84.8
N.A.
63.8
N.A.
53.4
67
57
70.6
P-Site Identity:
100
100
100
100
N.A.
80
86.6
N.A.
N.A.
86.6
N.A.
0
N.A.
20
0
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
80
86.6
N.A.
N.A.
93.3
N.A.
0
N.A.
46.6
13.3
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
8
8
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
24
47
0
0
0
0
0
16
% C
% Asp:
0
8
8
8
0
0
0
8
16
54
16
54
8
8
8
% D
% Glu:
8
0
0
8
0
0
0
0
0
8
0
0
0
8
0
% E
% Phe:
0
0
8
54
0
0
8
0
8
0
39
0
8
0
0
% F
% Gly:
16
24
0
0
8
16
62
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
24
0
0
0
0
0
0
16
0
8
% I
% Lys:
8
0
0
0
0
8
8
0
0
0
8
8
0
8
8
% K
% Leu:
0
0
8
8
8
47
0
8
8
8
16
16
54
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
8
0
0
0
8
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% N
% Pro:
0
16
0
0
0
0
8
0
0
0
0
0
0
0
54
% P
% Gln:
54
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
54
0
0
8
0
0
0
0
0
0
16
70
0
% R
% Ser:
0
31
8
16
62
0
0
0
8
0
0
0
0
0
8
% S
% Thr:
0
0
0
0
8
0
0
0
0
0
8
8
0
0
0
% T
% Val:
0
0
0
0
8
0
0
8
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
0
0
16
54
8
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _