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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LACE1
All Species:
28.18
Human Site:
S180
Identified Species:
56.36
UniProt:
Q8WV93
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WV93
NP_660358.2
481
54845
S180
R
I
H
R
L
K
Q
S
L
P
K
R
K
P
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093944
481
54837
S180
R
I
H
R
L
K
Q
S
L
P
K
R
K
P
G
Dog
Lupus familis
XP_539073
457
52718
S156
R
I
H
R
L
K
K
S
L
P
K
R
K
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3V384
480
54295
S180
R
I
H
H
L
K
Q
S
L
P
K
R
K
A
G
Rat
Rattus norvegicus
Q32PX9
480
54484
S180
R
I
H
R
L
K
Q
S
L
P
K
R
K
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511224
853
93854
S552
R
I
H
R
L
K
Q
S
L
P
K
R
K
P
G
Chicken
Gallus gallus
XP_419799
492
56007
S189
R
I
H
R
L
K
Q
S
L
P
K
R
K
P
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5TYS0
503
57582
Q202
R
R
I
H
K
L
K
Q
S
L
P
K
R
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
S281
K
L
A
G
E
S
E
S
N
L
R
K
A
F
E
Honey Bee
Apis mellifera
XP_624398
436
50701
L146
R
D
V
S
S
T
K
L
Q
P
F
D
P
I
P
Nematode Worm
Caenorhab. elegans
NP_491986
445
51394
K144
E
L
K
M
Q
S
N
K
A
R
G
K
F
D
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32317
509
58246
Q172
S
H
E
I
V
R
E
Q
N
L
K
E
L
G
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.6
86.2
N.A.
86.9
85.8
N.A.
48.7
73.7
N.A.
49.5
N.A.
20.3
46.3
39.7
N.A.
Protein Similarity:
100
N.A.
97.7
90.4
N.A.
91.6
90.8
N.A.
52.7
83.9
N.A.
67.1
N.A.
32.5
62.9
56.1
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
86.6
93.3
N.A.
100
100
N.A.
6.6
N.A.
6.6
13.3
0
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
86.6
93.3
N.A.
100
100
N.A.
26.6
N.A.
40
20
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
9
0
0
0
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
0
0
0
9
0
9
9
% D
% Glu:
9
0
9
0
9
0
17
0
0
0
0
9
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
0
9
9
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
9
0
0
9
59
% G
% His:
0
9
59
17
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
59
9
9
0
0
0
0
0
0
0
0
0
9
9
% I
% Lys:
9
0
9
0
9
59
25
9
0
0
67
25
59
0
0
% K
% Leu:
0
17
0
0
59
9
0
9
59
25
0
0
9
0
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
17
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
67
9
0
9
42
17
% P
% Gln:
0
0
0
0
9
0
50
17
9
0
0
0
0
0
0
% Q
% Arg:
75
9
0
50
0
9
0
0
0
9
9
59
9
9
0
% R
% Ser:
9
0
0
9
9
17
0
67
9
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
9
0
9
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _