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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LACE1
All Species:
21.21
Human Site:
T465
Identified Species:
42.42
UniProt:
Q8WV93
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WV93
NP_660358.2
481
54845
T465
Q
R
T
I
S
R
L
T
E
M
Q
T
E
Q
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093944
481
54837
T465
Q
R
T
I
S
R
L
T
E
M
Q
T
E
Q
Y
Dog
Lupus familis
XP_539073
457
52718
T441
Q
R
T
L
S
R
L
T
E
M
Q
T
E
Q
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q3V384
480
54295
E465
R
T
I
S
R
L
T
E
M
Q
T
E
Q
Y
W
Rat
Rattus norvegicus
Q32PX9
480
54484
E465
R
T
L
S
R
L
T
E
M
Q
T
E
Q
Y
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511224
853
93854
T837
Q
R
T
I
S
R
L
T
E
M
Q
N
E
Q
Y
Chicken
Gallus gallus
XP_419799
492
56007
T474
Q
R
T
I
S
R
L
T
E
M
Q
T
E
Q
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5TYS0
503
57582
A487
Q
R
T
V
S
R
L
A
E
M
Q
T
E
Q
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
T676
L
T
Y
I
A
K
V
T
Q
G
F
S
G
A
D
Honey Bee
Apis mellifera
XP_624398
436
50701
L420
F
D
R
T
I
S
R
L
S
E
M
Q
T
T
Q
Nematode Worm
Caenorhab. elegans
NP_491986
445
51394
T419
E
A
F
A
Y
S
R
T
V
S
R
L
Y
E
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32317
509
58246
L481
K
K
S
Q
M
F
A
L
D
E
E
R
F
A
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.6
86.2
N.A.
86.9
85.8
N.A.
48.7
73.7
N.A.
49.5
N.A.
20.3
46.3
39.7
N.A.
Protein Similarity:
100
N.A.
97.7
90.4
N.A.
91.6
90.8
N.A.
52.7
83.9
N.A.
67.1
N.A.
32.5
62.9
56.1
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
0
0
N.A.
93.3
100
N.A.
86.6
N.A.
13.3
0
6.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
20
20
N.A.
93.3
100
N.A.
93.3
N.A.
46.6
0
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
9
0
9
9
0
0
0
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
9
% D
% Glu:
9
0
0
0
0
0
0
17
50
17
9
17
50
9
0
% E
% Phe:
9
0
9
0
0
9
0
0
0
0
9
0
9
0
9
% F
% Gly:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
42
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
9
9
0
17
50
17
0
0
0
9
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
17
50
9
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
50
0
0
9
0
0
0
0
9
17
50
9
17
50
9
% Q
% Arg:
17
50
9
0
17
50
17
0
0
0
9
9
0
0
0
% R
% Ser:
0
0
9
17
50
17
0
0
9
9
0
9
0
0
0
% S
% Thr:
0
25
50
9
0
0
17
59
0
0
17
42
9
9
0
% T
% Val:
0
0
0
9
0
0
9
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% W
% Tyr:
0
0
9
0
9
0
0
0
0
0
0
0
9
17
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _