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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFAND2B
All Species:
19.39
Human Site:
S135
Identified Species:
32.82
UniProt:
Q8WV99
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WV99
NP_620157.1
257
28023
S135
H
P
L
D
H
D
C
S
G
E
G
H
P
T
S
Chimpanzee
Pan troglodytes
XP_001146767
268
29303
S146
H
P
L
D
H
D
C
S
G
E
G
H
P
T
S
Rhesus Macaque
Macaca mulatta
XP_001097402
257
28053
S135
H
P
L
D
H
D
C
S
G
E
G
H
P
T
S
Dog
Lupus familis
XP_853229
234
25257
G112
P
L
D
H
D
C
S
G
Q
S
H
P
T
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q91X58
257
27877
S135
H
P
L
D
H
E
C
S
G
E
G
H
Q
T
S
Rat
Rattus norvegicus
Q4KLG9
257
27907
S135
H
P
L
D
H
D
C
S
G
E
G
H
P
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511763
179
20282
C57
K
D
V
Q
V
P
I
C
P
L
C
N
I
P
V
Chicken
Gallus gallus
XP_422896
175
19457
V54
A
Y
K
K
N
V
Q
V
P
V
C
P
L
C
N
Frog
Xenopus laevis
NP_001088841
263
28606
K135
H
P
L
D
H
D
C
K
G
K
S
A
P
I
S
Zebra Danio
Brachydanio rerio
NP_956811
282
31041
S155
A
L
M
R
A
Q
G
S
S
S
S
N
T
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097074
253
27615
K131
H
T
S
D
H
D
C
K
P
V
P
A
S
S
T
Honey Bee
Apis mellifera
XP_395779
208
23514
D87
I
D
N
E
C
Q
S
D
L
K
T
S
S
Q
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793584
293
32671
S169
A
G
S
S
S
S
S
S
R
N
Q
A
R
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCM4
249
27742
L127
D
C
S
I
D
H
C
L
K
H
R
F
G
P
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
96.8
78.5
N.A.
90.2
91
N.A.
45.1
43.5
62.3
56.3
N.A.
40.8
42.7
N.A.
36.8
Protein Similarity:
100
92.5
98.4
82.4
N.A.
94.9
94.9
N.A.
56.4
54
74.9
71.9
N.A.
57.9
57.2
N.A.
55.9
P-Site Identity:
100
100
100
0
N.A.
86.6
100
N.A.
0
0
66.6
6.6
N.A.
33.3
0
N.A.
6.6
P-Site Similarity:
100
100
100
6.6
N.A.
93.3
100
N.A.
13.3
13.3
73.3
26.6
N.A.
46.6
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
0
0
8
0
0
0
0
0
0
22
0
8
8
% A
% Cys:
0
8
0
0
8
8
58
8
0
0
15
0
0
8
0
% C
% Asp:
8
15
8
50
15
43
0
8
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
8
0
8
0
0
0
36
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
8
0
0
0
0
8
8
43
0
36
0
8
0
0
% G
% His:
50
0
0
8
50
8
0
0
0
8
8
36
0
0
0
% H
% Ile:
8
0
0
8
0
0
8
0
0
0
0
0
8
8
0
% I
% Lys:
8
0
8
8
0
0
0
15
8
15
0
0
0
0
8
% K
% Leu:
0
15
43
0
0
0
0
8
8
8
0
0
8
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
0
0
0
0
8
0
15
0
0
8
% N
% Pro:
8
43
0
0
0
8
0
0
22
0
8
15
36
22
0
% P
% Gln:
0
0
0
8
0
15
8
0
8
0
8
0
8
8
8
% Q
% Arg:
0
0
0
8
0
0
0
0
8
0
8
0
8
0
8
% R
% Ser:
0
0
22
8
8
8
22
50
8
15
15
8
15
15
43
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
8
0
15
36
8
% T
% Val:
0
0
8
0
8
8
0
8
0
15
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _