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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFAND2B
All Species:
22.73
Human Site:
S246
Identified Species:
38.46
UniProt:
Q8WV99
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WV99
NP_620157.1
257
28023
S246
Y
Q
R
Q
Q
A
Q
S
R
S
S
K
P
S
N
Chimpanzee
Pan troglodytes
XP_001146767
268
29303
S257
Y
Q
R
Q
Q
A
Q
S
R
S
S
K
P
S
N
Rhesus Macaque
Macaca mulatta
XP_001097402
257
28053
S246
Y
Q
Q
Q
Q
A
Q
S
R
S
S
K
P
S
N
Dog
Lupus familis
XP_853229
234
25257
S223
Y
R
Q
Q
Q
A
Q
S
R
S
L
K
P
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q91X58
257
27877
S246
Y
Q
Q
Q
Q
A
Q
S
R
S
L
K
P
S
N
Rat
Rattus norvegicus
Q4KLG9
257
27907
S246
Y
Q
Q
Q
Q
A
Q
S
R
S
L
K
P
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511763
179
20282
W168
S
S
K
L
P
S
S
W
L
P
K
Q
F
R
C
Chicken
Gallus gallus
XP_422896
175
19457
S165
T
G
A
I
A
V
P
S
H
G
S
M
Q
H
N
Frog
Xenopus laevis
NP_001088841
263
28606
Q246
E
E
E
Y
R
Q
Q
Q
A
I
Q
G
Q
N
R
Zebra Danio
Brachydanio rerio
NP_956811
282
31041
Q266
E
E
E
Y
R
R
Q
Q
Q
R
Q
Q
G
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097074
253
27615
Q242
A
V
G
G
G
G
N
Q
Q
G
N
G
K
D
K
Honey Bee
Apis mellifera
XP_395779
208
23514
P198
R
Q
A
L
E
D
A
P
S
G
N
R
D
R
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793584
293
32671
E280
A
R
A
L
A
A
S
E
E
E
E
R
N
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCM4
249
27742
H238
D
P
V
D
L
L
K
H
I
D
K
D
H
R
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
96.8
78.5
N.A.
90.2
91
N.A.
45.1
43.5
62.3
56.3
N.A.
40.8
42.7
N.A.
36.8
Protein Similarity:
100
92.5
98.4
82.4
N.A.
94.9
94.9
N.A.
56.4
54
74.9
71.9
N.A.
57.9
57.2
N.A.
55.9
P-Site Identity:
100
100
93.3
80
N.A.
86.6
86.6
N.A.
0
20
6.6
6.6
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
20
20
26.6
33.3
N.A.
13.3
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
22
0
15
50
8
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% C
% Asp:
8
0
0
8
0
8
0
0
0
8
0
8
8
8
0
% D
% Glu:
15
15
15
0
8
0
0
8
8
8
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
8
8
8
8
8
0
0
0
22
0
15
8
8
8
% G
% His:
0
0
0
0
0
0
0
8
8
0
0
0
8
8
0
% H
% Ile:
0
0
0
8
0
0
0
0
8
8
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
8
0
0
0
15
43
8
0
8
% K
% Leu:
0
0
0
22
8
8
0
0
8
0
22
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
15
0
8
8
50
% N
% Pro:
0
8
0
0
8
0
8
8
0
8
0
0
43
0
0
% P
% Gln:
0
43
29
43
43
8
58
22
15
0
15
15
15
0
0
% Q
% Arg:
8
15
15
0
15
8
0
0
43
8
0
15
0
29
15
% R
% Ser:
8
8
0
0
0
8
15
50
8
43
29
0
0
43
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
8
0
0
8
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
43
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _