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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHTF18
All Species:
8.48
Human Site:
S277
Identified Species:
14.36
UniProt:
Q8WVB6
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVB6
NP_071375.1
975
107383
S277
P
T
D
G
Q
D
A
S
S
H
C
L
W
V
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001087813
975
107675
C277
P
A
D
G
Q
D
T
C
T
H
C
L
W
V
D
Dog
Lupus familis
XP_547205
952
105405
S241
L
A
N
S
P
D
G
S
Q
H
C
L
W
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIW9
969
108119
A272
P
A
P
G
Q
N
T
A
Q
H
C
L
W
V
D
Rat
Rattus norvegicus
NP_001099243
968
107973
A270
P
G
P
G
Q
E
T
A
Q
H
C
L
W
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519056
506
55652
Chicken
Gallus gallus
XP_414833
951
106607
T260
D
T
G
E
E
E
P
T
P
H
C
L
W
V
D
Frog
Xenopus laevis
Q6NU40
1000
113204
S297
E
D
D
E
D
E
P
S
S
H
S
L
W
V
D
Zebra Danio
Brachydanio rerio
NP_001103572
957
108656
A275
G
D
S
G
E
D
E
A
S
S
R
L
W
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_787969
993
111731
E317
V
N
S
N
A
N
S
E
P
G
R
L
W
V
D
Honey Bee
Apis mellifera
XP_001122463
755
86984
F192
Y
I
R
V
K
M
P
F
S
Q
I
K
A
E
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780624
1005
112781
G286
P
E
E
D
D
G
K
G
N
R
G
L
W
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_171966
954
107988
R254
L
S
D
E
Q
T
N
R
E
V
L
L
W
L
K
Baker's Yeast
Sacchar. cerevisiae
P49956
741
84355
K177
P
L
K
R
P
P
K
K
I
L
L
L
H
G
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.5
73
N.A.
76
77.2
N.A.
20.2
53.7
53.4
46.6
N.A.
32.4
27.8
N.A.
34.6
Protein Similarity:
100
N.A.
95.9
79.6
N.A.
81.7
82.7
N.A.
29.8
68.7
71
63.3
N.A.
52.5
45.3
N.A.
54.1
P-Site Identity:
100
N.A.
73.3
53.3
N.A.
60
60
N.A.
0
46.6
53.3
46.6
N.A.
26.6
6.6
N.A.
33.3
P-Site Similarity:
100
N.A.
80
60
N.A.
73.3
73.3
N.A.
0
66.6
60
60
N.A.
40
13.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
39.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
22
0
0
8
0
8
22
0
0
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
43
0
0
0
0
% C
% Asp:
8
15
29
8
15
29
0
0
0
0
0
0
0
0
72
% D
% Glu:
8
8
8
22
15
22
8
8
8
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
8
8
36
0
8
8
8
0
8
8
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
50
0
0
8
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
8
0
8
0
0
0
0
% I
% Lys:
0
0
8
0
8
0
15
8
0
0
0
8
0
0
8
% K
% Leu:
15
8
0
0
0
0
0
0
0
8
15
86
0
8
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
8
0
15
8
0
8
0
0
0
0
0
0
% N
% Pro:
43
0
15
0
15
8
22
0
15
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
36
0
0
0
22
8
0
0
0
0
0
% Q
% Arg:
0
0
8
8
0
0
0
8
0
8
15
0
0
0
0
% R
% Ser:
0
8
15
8
0
0
8
22
29
8
8
0
0
0
0
% S
% Thr:
0
15
0
0
0
8
22
8
8
0
0
0
0
0
0
% T
% Val:
8
0
0
8
0
0
0
0
0
8
0
0
0
72
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
79
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _