KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHTF18
All Species:
34.24
Human Site:
Y838
Identified Species:
57.95
UniProt:
Q8WVB6
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVB6
NP_071375.1
975
107383
Y838
P
A
R
K
P
L
T
Y
Q
T
K
Q
L
I
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001087813
975
107675
Y838
P
A
R
K
P
L
T
Y
Q
A
K
Q
L
I
A
Dog
Lupus familis
XP_547205
952
105405
Y810
P
A
R
K
P
L
T
Y
Q
A
K
Q
L
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIW9
969
108119
Y832
P
A
R
K
P
L
T
Y
Q
A
K
Q
L
I
A
Rat
Rattus norvegicus
NP_001099243
968
107973
Y831
P
A
R
K
P
L
T
Y
Q
A
K
Q
L
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519056
506
55652
N411
I
A
K
H
A
G
Y
N
V
V
E
M
N
A
S
Chicken
Gallus gallus
XP_414833
951
106607
Y821
P
A
R
K
Q
L
T
Y
Q
A
K
Q
L
I
A
Frog
Xenopus laevis
Q6NU40
1000
113204
Y864
P
V
R
K
P
L
T
Y
Q
T
K
Q
L
I
A
Zebra Danio
Brachydanio rerio
NP_001103572
957
108656
Y825
P
P
R
R
Q
L
T
Y
Q
V
K
Q
L
I
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_787969
993
111731
Y874
Y
T
G
L
S
L
P
Y
F
S
R
Q
L
I
A
Honey Bee
Apis mellifera
XP_001122463
755
86984
A661
I
L
V
Q
E
L
E
A
E
R
L
R
R
A
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780624
1005
112781
Y864
P
P
V
R
Q
I
T
Y
A
A
K
Q
L
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_171966
954
107988
H806
A
M
K
Q
V
L
V
H
E
L
P
E
D
L
D
Baker's Yeast
Sacchar. cerevisiae
P49956
741
84355
K646
I
E
E
N
R
A
K
K
R
H
I
D
Q
V
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.5
73
N.A.
76
77.2
N.A.
20.2
53.7
53.4
46.6
N.A.
32.4
27.8
N.A.
34.6
Protein Similarity:
100
N.A.
95.9
79.6
N.A.
81.7
82.7
N.A.
29.8
68.7
71
63.3
N.A.
52.5
45.3
N.A.
54.1
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
6.6
86.6
93.3
73.3
N.A.
40
13.3
N.A.
53.3
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
26.6
86.6
93.3
80
N.A.
53.3
33.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
39.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
50
0
0
8
8
0
8
8
43
0
0
0
15
79
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
8
% D
% Glu:
0
8
8
0
8
0
8
0
15
0
8
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
8
0
8
0
0
0
0
0
% H
% Ile:
22
0
0
0
0
8
0
0
0
0
8
0
0
72
0
% I
% Lys:
0
0
15
50
0
0
8
8
0
0
65
0
0
0
0
% K
% Leu:
0
8
0
8
0
79
0
0
0
8
8
0
72
8
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
8
0
0
0
0
8
0
0
% N
% Pro:
65
15
0
0
43
0
8
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
15
22
0
0
0
58
0
0
72
8
0
0
% Q
% Arg:
0
0
58
15
8
0
0
0
8
8
8
8
8
0
0
% R
% Ser:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
8
% S
% Thr:
0
8
0
0
0
0
65
0
0
15
0
0
0
0
8
% T
% Val:
0
8
15
0
8
0
8
0
8
15
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
8
72
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _