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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LEO1
All Species:
10.61
Human Site:
S123
Identified Species:
21.21
UniProt:
Q8WVC0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVC0
NP_620147.1
666
75404
S123
D
E
D
E
G
H
R
S
D
G
G
S
H
H
S
Chimpanzee
Pan troglodytes
XP_001170061
606
67985
R83
G
S
D
N
H
S
E
R
S
D
N
R
S
E
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535485
665
75345
S123
D
E
D
E
G
H
R
S
D
G
G
S
H
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5XJE5
667
75623
S123
D
D
D
E
G
H
R
S
D
E
G
S
R
H
S
Rat
Rattus norvegicus
Q641X2
678
76939
E135
D
E
G
H
R
S
D
E
G
S
H
H
S
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512640
354
40227
Chicken
Gallus gallus
XP_413803
627
71376
H104
D
Q
S
D
V
D
Q
H
S
A
S
E
A
A
H
Frog
Xenopus laevis
Q52KV5
703
80388
K155
E
K
W
G
R
E
D
K
S
D
Q
S
D
E
E
Zebra Danio
Brachydanio rerio
Q6NYV9
696
76423
S123
S
E
R
S
G
N
Q
S
D
A
T
M
H
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94546
725
77404
R152
S
G
S
A
H
S
R
R
S
G
S
A
R
S
R
Honey Bee
Apis mellifera
XP_624295
603
67203
R80
S
P
V
R
S
D
S
R
H
S
S
I
G
S
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781595
591
67675
E68
E
E
E
V
H
E
E
E
E
G
E
G
E
Y
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
N.A.
97.7
N.A.
93.4
92.1
N.A.
47.5
78.8
70.9
60.3
N.A.
32.5
36.3
N.A.
42.7
Protein Similarity:
100
90.9
N.A.
99
N.A.
96.5
95.5
N.A.
49.7
86.7
82
69.8
N.A.
49.3
54.9
N.A.
59.4
P-Site Identity:
100
6.6
N.A.
100
N.A.
80
13.3
N.A.
0
6.6
6.6
33.3
N.A.
13.3
0
N.A.
13.3
P-Site Similarity:
100
13.3
N.A.
100
N.A.
86.6
20
N.A.
0
26.6
20
46.6
N.A.
20
6.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
17
0
9
9
9
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
42
9
34
9
0
17
17
0
34
17
0
0
9
0
9
% D
% Glu:
17
42
9
25
0
17
17
17
9
9
9
9
9
25
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
9
9
34
0
0
0
9
34
25
9
9
0
0
% G
% His:
0
0
0
9
25
25
0
9
9
0
9
9
25
25
9
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
9
0
9
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
17
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
9
9
17
0
34
25
0
0
0
9
17
0
9
% R
% Ser:
25
9
17
9
9
25
9
34
34
17
25
34
17
25
25
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% T
% Val:
0
0
9
9
9
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _