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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LEO1
All Species:
23.03
Human Site:
Y394
Identified Species:
46.06
UniProt:
Q8WVC0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVC0
NP_620147.1
666
75404
Y394
R
P
F
D
P
Q
Y
Y
E
D
E
F
E
D
E
Chimpanzee
Pan troglodytes
XP_001170061
606
67985
D346
D
E
N
G
L
P
Q
D
Q
Q
E
E
E
P
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535485
665
75345
Y393
R
P
F
D
P
Q
Y
Y
E
D
E
F
E
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5XJE5
667
75623
Y395
R
P
F
D
P
Q
Y
Y
E
D
E
F
E
D
E
Rat
Rattus norvegicus
Q641X2
678
76939
Y406
R
P
F
D
P
Q
Y
Y
E
D
E
F
E
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512640
354
40227
E94
Y
E
D
E
F
E
D
E
E
M
L
D
E
E
G
Chicken
Gallus gallus
XP_413803
627
71376
P367
D
L
Y
F
V
K
L
P
N
F
L
S
V
E
P
Frog
Xenopus laevis
Q52KV5
703
80388
Y425
R
P
F
D
P
Q
Y
Y
E
D
E
F
E
D
E
Zebra Danio
Brachydanio rerio
Q6NYV9
696
76423
T388
M
L
D
E
E
G
R
T
R
L
K
L
K
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94546
725
77404
Y416
H
P
F
D
P
E
T
Y
E
D
E
I
D
E
E
Honey Bee
Apis mellifera
XP_624295
603
67203
D343
E
T
Y
E
D
E
I
D
E
E
E
T
L
D
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781595
591
67675
N331
Y
H
F
A
K
L
P
N
F
L
S
V
E
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
N.A.
97.7
N.A.
93.4
92.1
N.A.
47.5
78.8
70.9
60.3
N.A.
32.5
36.3
N.A.
42.7
Protein Similarity:
100
90.9
N.A.
99
N.A.
96.5
95.5
N.A.
49.7
86.7
82
69.8
N.A.
49.3
54.9
N.A.
59.4
P-Site Identity:
100
13.3
N.A.
100
N.A.
100
100
N.A.
13.3
0
100
6.6
N.A.
60
26.6
N.A.
13.3
P-Site Similarity:
100
20
N.A.
100
N.A.
100
100
N.A.
33.3
20
100
26.6
N.A.
80
53.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
17
50
9
0
9
17
0
50
0
9
9
50
0
% D
% Glu:
9
17
0
25
9
25
0
9
67
9
67
9
67
25
67
% E
% Phe:
0
0
59
9
9
0
0
0
9
9
0
42
0
0
0
% F
% Gly:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
9
% G
% His:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
9
% I
% Lys:
0
0
0
0
9
9
0
0
0
0
9
0
9
0
0
% K
% Leu:
0
17
0
0
9
9
9
0
0
17
17
9
9
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
9
9
0
0
0
0
0
0
% N
% Pro:
0
50
0
0
50
9
9
9
0
0
0
0
0
9
9
% P
% Gln:
0
0
0
0
0
42
9
0
9
9
0
0
0
0
0
% Q
% Arg:
42
0
0
0
0
0
9
0
9
0
0
0
0
0
9
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% S
% Thr:
0
9
0
0
0
0
9
9
0
0
0
9
0
9
0
% T
% Val:
0
0
0
0
9
0
0
0
0
0
0
9
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
17
0
17
0
0
0
42
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _