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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LEO1
All Species:
18.18
Human Site:
Y575
Identified Species:
36.36
UniProt:
Q8WVC0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVC0
NP_620147.1
666
75404
Y575
S
Y
L
E
P
D
R
Y
D
E
E
E
E
G
E
Chimpanzee
Pan troglodytes
XP_001170061
606
67985
E519
P
D
R
Y
D
E
E
E
E
G
E
E
S
I
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535485
665
75345
Y574
S
Y
L
E
P
D
R
Y
D
E
E
E
E
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5XJE5
667
75623
Y576
S
Y
L
E
P
D
R
Y
D
E
E
E
E
G
E
Rat
Rattus norvegicus
Q641X2
678
76939
Y587
S
Y
L
E
P
D
R
Y
D
E
E
E
E
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512640
354
40227
D267
P
D
R
Y
D
D
E
D
E
G
E
E
S
I
S
Chicken
Gallus gallus
XP_413803
627
71376
Q540
A
S
I
R
R
E
S
Q
Q
R
R
M
R
E
K
Frog
Xenopus laevis
Q52KV5
703
80388
Y606
N
Y
L
E
P
D
R
Y
D
D
E
E
E
G
D
Zebra Danio
Brachydanio rerio
Q6NYV9
696
76423
G574
A
I
K
S
K
Y
K
G
G
G
G
L
R
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94546
725
77404
H598
G
G
T
S
S
Y
Q
H
D
E
G
S
D
D
E
Honey Bee
Apis mellifera
XP_624295
603
67203
G516
R
S
V
G
G
Y
G
G
D
T
Y
H
D
D
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781595
591
67675
Q504
L
R
A
S
L
R
R
Q
N
Q
Q
R
R
I
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
N.A.
97.7
N.A.
93.4
92.1
N.A.
47.5
78.8
70.9
60.3
N.A.
32.5
36.3
N.A.
42.7
Protein Similarity:
100
90.9
N.A.
99
N.A.
96.5
95.5
N.A.
49.7
86.7
82
69.8
N.A.
49.3
54.9
N.A.
59.4
P-Site Identity:
100
13.3
N.A.
100
N.A.
100
100
N.A.
20
0
80
6.6
N.A.
20
6.6
N.A.
6.6
P-Site Similarity:
100
26.6
N.A.
100
N.A.
100
100
N.A.
26.6
26.6
100
20
N.A.
40
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
0
0
17
50
0
9
59
9
0
0
17
17
9
% D
% Glu:
0
0
0
42
0
17
17
9
17
42
59
59
42
17
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
0
9
9
0
9
17
9
25
17
0
0
42
9
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% H
% Ile:
0
9
9
0
0
0
0
0
0
0
0
0
0
25
0
% I
% Lys:
0
0
9
0
9
0
9
0
0
0
0
0
0
0
9
% K
% Leu:
9
0
42
0
9
0
0
0
0
0
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
17
0
0
0
42
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
17
9
9
9
0
0
0
0
% Q
% Arg:
9
9
17
9
9
9
50
0
0
9
9
9
25
0
9
% R
% Ser:
34
17
0
25
9
0
9
0
0
0
0
9
17
0
17
% S
% Thr:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
42
0
17
0
25
0
42
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _