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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF141 All Species: 20.61
Human Site: T135 Identified Species: 50.37
UniProt: Q8WVD5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WVD5 NP_057506.2 230 25535 T135 D E N S S S V T S C Q A S L W
Chimpanzee Pan troglodytes XP_508282 230 25503 T135 D E N S S S V T S C H A S L W
Rhesus Macaque Macaca mulatta XP_001094332 195 21601 A114 Y K D I T S Q A A G V L A Q S
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q99MB7 230 25510 T135 D E N P S S V T S C Q A S L W
Rat Rattus norvegicus Q6IV57 230 25452 T135 D G N P S S V T S C Q A S L W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507444 230 25173 S135 A E N L S S G S S C Q A S L W
Chicken Gallus gallus Q5ZM74 230 25375 S135 A E S L T S V S S S Q A S L W
Frog Xenopus laevis Q6NRX0 397 43453 A241 N R K E T K K A I S Q L Q L H
Zebra Danio Brachydanio rerio Q6IV56 222 24417 W134 D T C Q A S M W M G R V K Q L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_510276 201 23786 T120 S T S Q F I L T Q T S D V E G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 81.3 N.A. N.A. 99.1 98.2 N.A. 92.1 84.3 20.6 76 N.A. N.A. N.A. 23.4 N.A.
Protein Similarity: 100 98.6 83.9 N.A. N.A. 99.5 99.1 N.A. 94.7 92.6 34.5 86.5 N.A. N.A. N.A. 45.6 N.A.
P-Site Identity: 100 93.3 6.6 N.A. N.A. 93.3 86.6 N.A. 73.3 60 13.3 13.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 93.3 40 N.A. N.A. 93.3 86.6 N.A. 80 80 26.6 33.3 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 0 0 10 0 0 20 10 0 0 60 10 0 0 % A
% Cys: 0 0 10 0 0 0 0 0 0 50 0 0 0 0 0 % C
% Asp: 50 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 50 0 10 0 0 0 0 0 0 0 0 0 10 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 10 0 0 20 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % H
% Ile: 0 0 0 10 0 10 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 10 10 0 0 10 10 0 0 0 0 0 10 0 0 % K
% Leu: 0 0 0 20 0 0 10 0 0 0 0 20 0 70 10 % L
% Met: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % M
% Asn: 10 0 50 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 20 0 0 10 0 10 0 60 0 10 20 0 % Q
% Arg: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 10 0 20 20 50 80 0 20 60 20 10 0 60 0 10 % S
% Thr: 0 20 0 0 30 0 0 50 0 10 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 50 0 0 0 10 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 60 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _