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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM170A All Species: 20.3
Human Site: S37 Identified Species: 40.61
UniProt: Q8WVE7 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WVE7 NP_660297.1 144 15250 S37 N G T L C P N S T S L C S F P
Chimpanzee Pan troglodytes XP_001140581 356 39540 S37 N G T L C P N S T S L C S F P
Rhesus Macaque Macaca mulatta XP_001109807 356 39508 S37 N G T L C P N S T S L C S F P
Dog Lupus familis XP_850505 144 15213 S37 N G T L C P N S T S L C S F P
Cat Felis silvestris
Mouse Mus musculus Q9D342 144 15206 S37 N G T L C P N S T S L C S F P
Rat Rattus norvegicus Q7TQ79 132 14398 T26 L S L W A H G T V L R N L T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517799 251 27235 I144 N E T L C P N I T A L C S F P
Chicken Gallus gallus Q5ZM31 138 14772 S32 G N G T T Y S S P L S T F P E
Frog Xenopus laevis Q6DF87 142 15110 A36 N V T D C Q R A T L C S F P E
Zebra Danio Brachydanio rerio A3KPL7 145 15677 N38 N N T T C G N N T S L C D F S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120796 134 14922 Y27 I N T G N V F Y M P L T S F A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001178443 123 13567 N17 S V I S L K S N P L D D W I E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.7 31.7 96.5 N.A. 95.8 45.1 N.A. 52.1 81.9 83.3 61.3 N.A. N.A. 43 N.A. 42.3
Protein Similarity: 100 35.9 35.9 98.6 N.A. 99.3 61.1 N.A. 54.5 87.5 89.5 71.7 N.A. N.A. 59 N.A. 53.4
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 80 6.6 26.6 60 N.A. N.A. 26.6 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 6.6 N.A. 86.6 13.3 33.3 66.6 N.A. N.A. 26.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 0 9 0 9 0 0 0 0 9 % A
% Cys: 0 0 0 0 67 0 0 0 0 0 9 59 0 0 0 % C
% Asp: 0 0 0 9 0 0 0 0 0 0 9 9 9 0 0 % D
% Glu: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 34 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 17 67 0 % F
% Gly: 9 42 9 9 0 9 9 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 9 0 0 0 0 9 0 0 0 0 0 9 0 % I
% Lys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 0 9 50 9 0 0 0 0 34 67 0 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 67 25 0 0 9 0 59 17 0 0 0 9 0 0 0 % N
% Pro: 0 0 0 0 0 50 0 0 17 9 0 0 0 17 50 % P
% Gln: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 9 0 0 0 9 0 0 0 0 % R
% Ser: 9 9 0 9 0 0 17 50 0 50 9 9 59 0 9 % S
% Thr: 0 0 75 17 9 0 0 9 67 0 0 17 0 9 0 % T
% Val: 0 17 0 0 0 9 0 0 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 0 0 0 9 0 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _