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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM170A
All Species:
22.73
Human Site:
Y78
Identified Species:
45.45
UniProt:
Q8WVE7
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVE7
NP_660297.1
144
15250
Y78
F
T
L
R
H
H
K
Y
G
R
F
M
S
V
S
Chimpanzee
Pan troglodytes
XP_001140581
356
39540
Y78
F
T
L
R
H
H
K
Y
G
G
E
Y
S
E
D
Rhesus Macaque
Macaca mulatta
XP_001109807
356
39508
Y78
F
T
L
R
H
H
K
Y
G
G
E
Y
S
E
D
Dog
Lupus familis
XP_850505
144
15213
Y78
F
T
L
R
H
H
K
Y
G
R
F
M
S
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D342
144
15206
Y78
F
T
L
R
H
H
K
Y
G
R
F
M
S
V
S
Rat
Rattus norvegicus
Q7TQ79
132
14398
G67
M
L
Q
R
H
R
Q
G
R
V
L
S
I
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517799
251
27235
Y185
F
T
L
R
H
H
K
Y
G
R
F
M
S
V
S
Chicken
Gallus gallus
Q5ZM31
138
14772
G73
T
L
R
H
H
K
Y
G
R
F
M
S
V
S
L
Frog
Xenopus laevis
Q6DF87
142
15110
G77
T
L
R
H
H
K
Y
G
R
F
M
S
V
G
I
Zebra Danio
Brachydanio rerio
A3KPL7
145
15677
V79
A
T
L
R
R
H
K
V
A
R
F
F
P
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120796
134
14922
Y68
A
T
L
R
Q
H
K
Y
G
K
F
F
P
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178443
123
13567
G58
A
L
R
K
H
K
I
G
R
L
Y
S
L
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.7
31.7
96.5
N.A.
95.8
45.1
N.A.
52.1
81.9
83.3
61.3
N.A.
N.A.
43
N.A.
42.3
Protein Similarity:
100
35.9
35.9
98.6
N.A.
99.3
61.1
N.A.
54.5
87.5
89.5
71.7
N.A.
N.A.
59
N.A.
53.4
P-Site Identity:
100
66.6
66.6
100
N.A.
100
13.3
N.A.
100
6.6
6.6
46.6
N.A.
N.A.
53.3
N.A.
6.6
P-Site Similarity:
100
66.6
66.6
100
N.A.
100
33.3
N.A.
100
6.6
6.6
53.3
N.A.
N.A.
66.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
17
0
0
17
0
% E
% Phe:
50
0
0
0
0
0
0
0
0
17
50
17
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
34
59
17
0
0
0
9
9
% G
% His:
0
0
0
17
84
67
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
0
0
9
9
9
% I
% Lys:
0
0
0
9
0
25
67
0
0
9
0
0
0
0
0
% K
% Leu:
0
34
67
0
0
0
0
0
0
9
9
0
9
25
17
% L
% Met:
9
0
0
0
0
0
0
0
0
0
17
34
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% P
% Gln:
0
0
9
0
9
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
25
75
9
9
0
0
34
42
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
34
50
9
34
% S
% Thr:
17
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
9
0
9
0
0
17
34
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
17
59
0
0
9
17
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _