KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCTD4
All Species:
13.64
Human Site:
T240
Identified Species:
33.33
UniProt:
Q8WVF5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVF5
NP_940686.2
259
29967
T240
K
C
G
F
R
L
L
T
S
L
D
C
S
K
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542575
259
29919
T240
K
C
G
F
R
L
L
T
S
L
D
C
S
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7X1
259
29960
T240
K
C
G
F
R
L
L
T
S
L
D
C
S
K
G
Rat
Rattus norvegicus
Q8R4G8
257
29416
G219
Q
R
G
F
E
I
V
G
S
C
G
G
G
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514097
259
29820
T240
K
C
G
F
R
L
L
T
S
L
D
C
S
K
G
Chicken
Gallus gallus
Q5ZJP7
289
33209
V230
E
H
H
C
E
V
D
V
S
F
G
P
W
E
A
Frog
Xenopus laevis
Q6DCX3
255
29156
A219
Q
K
G
F
H
V
A
A
S
C
G
G
G
V
D
Zebra Danio
Brachydanio rerio
Q6DG99
237
27614
M213
R
N
T
R
V
H
H
M
S
E
R
A
N
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120405
250
27933
P230
G
N
S
E
Q
L
K
P
G
V
D
F
E
E
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001179882
139
16035
K121
E
R
D
T
Q
D
G
K
W
R
I
F
G
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.6
N.A.
97.3
23.5
N.A.
94.2
24.5
23.5
27
N.A.
N.A.
28.9
N.A.
25.8
Protein Similarity:
100
N.A.
N.A.
99.6
N.A.
99.2
43.2
N.A.
98.4
41.5
41.3
45.1
N.A.
N.A.
46.3
N.A.
39.7
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
20
N.A.
100
6.6
20
6.6
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
40
N.A.
100
26.6
33.3
26.6
N.A.
N.A.
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
10
0
0
0
10
0
0
10
% A
% Cys:
0
40
0
10
0
0
0
0
0
20
0
40
0
0
0
% C
% Asp:
0
0
10
0
0
10
10
0
0
0
50
0
0
0
20
% D
% Glu:
20
0
0
10
20
0
0
0
0
10
0
0
10
30
0
% E
% Phe:
0
0
0
60
0
0
0
0
0
10
0
20
0
0
0
% F
% Gly:
10
0
60
0
0
0
10
10
10
0
30
20
30
0
40
% G
% His:
0
10
10
0
10
10
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% I
% Lys:
40
10
0
0
0
0
10
10
0
0
0
0
0
40
0
% K
% Leu:
0
0
0
0
0
50
40
0
0
40
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
20
0
0
0
0
0
0
0
0
0
0
10
0
20
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% P
% Gln:
20
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
20
0
10
40
0
0
0
0
10
10
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
0
80
0
0
0
40
10
10
% S
% Thr:
0
0
10
10
0
0
0
40
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
20
10
10
0
10
0
0
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _