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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCTD4
All Species:
23.03
Human Site:
T46
Identified Species:
56.3
UniProt:
Q8WVF5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVF5
NP_940686.2
259
29967
T46
V
G
G
Y
L
Y
I
T
Q
K
Q
T
L
T
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542575
259
29919
T46
V
G
G
Y
L
Y
I
T
Q
K
Q
T
L
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7X1
259
29960
T46
V
G
G
Y
L
Y
I
T
Q
K
Q
T
L
T
K
Rat
Rattus norvegicus
Q8R4G8
257
29416
S43
V
G
G
H
M
Y
T
S
S
L
A
T
L
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514097
259
29820
T46
V
G
G
Y
L
Y
V
T
Q
K
Q
T
L
T
R
Chicken
Gallus gallus
Q5ZJP7
289
33209
T64
V
G
G
M
H
F
T
T
R
L
S
T
L
R
R
Frog
Xenopus laevis
Q6DCX3
255
29156
S43
V
G
G
H
M
Y
T
S
S
L
A
T
L
T
K
Zebra Danio
Brachydanio rerio
Q6DG99
237
27614
D59
A
Q
G
N
Y
F
I
D
R
D
G
T
L
F
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120405
250
27933
A43
R
E
S
D
S
H
L
A
A
L
F
S
G
K
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001179882
139
16035
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.6
N.A.
97.3
23.5
N.A.
94.2
24.5
23.5
27
N.A.
N.A.
28.9
N.A.
25.8
Protein Similarity:
100
N.A.
N.A.
99.6
N.A.
99.2
43.2
N.A.
98.4
41.5
41.3
45.1
N.A.
N.A.
46.3
N.A.
39.7
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
53.3
N.A.
86.6
40
53.3
26.6
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
73.3
N.A.
100
60
73.3
46.6
N.A.
N.A.
20
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
10
10
0
20
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
10
0
10
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
20
0
0
0
0
10
0
0
10
0
% F
% Gly:
0
70
80
0
0
0
0
0
0
0
10
0
10
0
0
% G
% His:
0
0
0
20
10
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
40
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
40
0
0
0
10
50
% K
% Leu:
0
0
0
0
40
0
10
0
0
40
0
0
80
0
0
% L
% Met:
0
0
0
10
20
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
40
0
40
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
20
0
0
0
0
10
30
% R
% Ser:
0
0
10
0
10
0
0
20
20
0
10
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
30
50
0
0
0
80
0
60
10
% T
% Val:
70
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
40
10
60
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _