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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP1R1C All Species: 29.7
Human Site: S65 Identified Species: 72.59
UniProt: Q8WVI7 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WVI7 NP_001074014.1 109 12346 S65 Q G E L Q N A S P K Q R K Q S
Chimpanzee Pan troglodytes XP_001159034 116 13161 S72 Q G E L Q N A S P K Q R K Q S
Rhesus Macaque Macaca mulatta XP_001101481 109 12314 S65 Q G E S Q N A S P K Q R K Q S
Dog Lupus familis XP_850516 205 22996 S97 L Q S I S N L S E N Q A S E E
Cat Felis silvestris
Mouse Mus musculus Q8BKK4 108 12284 S64 T Q E S Q N A S P K Q R K Q S
Rat Rattus norvegicus P19103 171 18719 S67 L K S T L S M S P R Q R K K M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515784 109 12019 S65 Q G E S Q N A S P K Q R K Q S
Chicken Gallus gallus XP_421970 109 12415 S65 Q A E C Q S S S P K Q R K Q S
Frog Xenopus laevis NP_001082695 185 20793 S65 L Q K S L S M S P H Q R K K M
Zebra Danio Brachydanio rerio NP_001002538 171 18448 S66 E A Q N A Q L S P A Q R K Q S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93 94.5 25.8 N.A. 84.4 35 N.A. 80.7 77.9 27.5 37.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 93 97.2 36 N.A. 89.9 47.3 N.A. 88.9 88 42.7 47.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 20 N.A. 80 33.3 N.A. 93.3 73.3 33.3 46.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 33.3 N.A. 80 53.3 N.A. 93.3 86.6 53.3 60 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 0 0 10 0 50 0 0 10 0 10 0 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 60 0 0 0 0 0 10 0 0 0 0 10 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 40 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 10 0 0 0 0 0 0 60 0 0 90 20 0 % K
% Leu: 30 0 0 20 20 0 20 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 20 0 0 0 0 0 0 0 20 % M
% Asn: 0 0 0 10 0 60 0 0 0 10 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 90 0 0 0 0 0 0 % P
% Gln: 50 30 10 0 60 10 0 0 0 0 100 0 0 70 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 10 0 90 0 0 0 % R
% Ser: 0 0 20 40 10 30 10 100 0 0 0 0 10 0 70 % S
% Thr: 10 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _