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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TWIST2
All Species:
14.85
Human Site:
S39
Identified Species:
27.22
UniProt:
Q8WVJ9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVJ9
NP_476527.1
160
18124
S39
K
R
R
Y
S
K
K
S
S
E
D
G
S
P
T
Chimpanzee
Pan troglodytes
Q8MI03
201
20743
G80
K
R
G
K
K
S
A
G
C
G
G
G
G
G
G
Rhesus Macaque
Macaca mulatta
XP_001103003
192
19946
G71
K
R
G
K
K
S
A
G
C
G
G
G
G
S
A
Dog
Lupus familis
XP_862780
160
17657
R39
G
K
R
G
G
R
K
R
R
S
S
R
R
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D030
160
18122
S39
K
R
R
Y
S
K
K
S
S
E
D
G
S
P
T
Rat
Rattus norvegicus
P97831
160
18106
S39
K
R
R
Y
S
K
K
S
S
E
D
G
S
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510876
214
24100
S93
K
R
R
Y
S
K
K
S
S
E
D
G
S
P
N
Chicken
Gallus gallus
P79782
183
20177
R63
P
M
V
M
V
K
Q
R
Q
A
A
N
A
R
E
Frog
Xenopus laevis
P13903
166
18778
P45
A
R
K
S
P
E
D
P
D
S
P
I
S
V
K
Zebra Danio
Brachydanio rerio
Q7ZSX3
265
30428
S88
F
S
Y
G
C
A
D
S
T
S
E
L
S
P
H
Tiger Blowfish
Takifugu rubipres
Q90YI8
371
40876
E177
N
S
L
G
G
E
S
E
Q
Y
S
M
Y
P
S
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001011637
366
42484
E226
K
S
S
T
I
E
N
E
S
E
T
E
S
N
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186660
334
37496
D212
C
Q
I
G
D
S
S
D
D
G
S
S
T
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.1
59.3
75
N.A.
99.3
100
N.A.
72.9
28.4
78.3
26.4
20.4
N.A.
31.9
N.A.
34.7
Protein Similarity:
100
72.1
65.6
81.2
N.A.
100
100
N.A.
73.8
39.8
85.5
37.7
30.7
N.A.
38.7
N.A.
41.3
P-Site Identity:
100
20
20
13.3
N.A.
100
100
N.A.
93.3
6.6
13.3
20
6.6
N.A.
26.6
N.A.
0
P-Site Similarity:
100
20
20
26.6
N.A.
100
100
N.A.
93.3
20
26.6
33.3
20
N.A.
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
16
0
0
8
8
0
8
0
24
% A
% Cys:
8
0
0
0
8
0
0
0
16
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
16
8
16
0
31
0
0
0
0
% D
% Glu:
0
0
0
0
0
24
0
16
0
39
8
8
0
0
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
16
31
16
0
0
16
0
24
16
47
16
16
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
8
0
8
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
54
8
8
16
16
39
39
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% L
% Met:
0
8
0
8
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
0
0
0
0
0
8
0
0
0
0
8
0
8
8
% N
% Pro:
8
0
0
0
8
0
0
8
0
0
8
0
0
47
0
% P
% Gln:
0
8
0
0
0
0
8
0
16
0
0
0
0
0
0
% Q
% Arg:
0
54
39
0
0
8
0
16
8
0
0
8
8
8
0
% R
% Ser:
0
24
8
8
31
24
16
39
39
24
24
8
54
16
16
% S
% Thr:
0
0
0
8
0
0
0
0
8
0
8
0
8
0
24
% T
% Val:
0
0
8
0
8
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
31
0
0
0
0
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _