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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TWIST2
All Species:
19.39
Human Site:
S44
Identified Species:
35.56
UniProt:
Q8WVJ9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVJ9
NP_476527.1
160
18124
S44
K
K
S
S
E
D
G
S
P
T
P
G
K
R
G
Chimpanzee
Pan troglodytes
Q8MI03
201
20743
G85
S
A
G
C
G
G
G
G
G
G
G
A
G
G
G
Rhesus Macaque
Macaca mulatta
XP_001103003
192
19946
G76
S
A
G
C
G
G
G
G
S
A
G
G
G
G
S
Dog
Lupus familis
XP_862780
160
17657
R44
R
K
R
R
S
S
R
R
S
A
G
G
G
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D030
160
18122
S44
K
K
S
S
E
D
G
S
P
T
P
G
K
R
G
Rat
Rattus norvegicus
P97831
160
18106
S44
K
K
S
S
E
D
G
S
P
T
P
G
K
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510876
214
24100
S98
K
K
S
S
E
D
G
S
P
N
P
G
K
R
G
Chicken
Gallus gallus
P79782
183
20177
A68
K
Q
R
Q
A
A
N
A
R
E
R
D
R
T
Q
Frog
Xenopus laevis
P13903
166
18778
S50
E
D
P
D
S
P
I
S
V
K
R
N
K
K
A
Zebra Danio
Brachydanio rerio
Q7ZSX3
265
30428
S93
A
D
S
T
S
E
L
S
P
H
R
D
G
G
L
Tiger Blowfish
Takifugu rubipres
Q90YI8
371
40876
Y182
E
S
E
Q
Y
S
M
Y
P
S
N
R
V
K
R
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001011637
366
42484
S231
E
N
E
S
E
T
E
S
N
A
S
S
T
K
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186660
334
37496
T217
S
S
D
D
G
S
S
T
G
S
G
S
L
S
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.1
59.3
75
N.A.
99.3
100
N.A.
72.9
28.4
78.3
26.4
20.4
N.A.
31.9
N.A.
34.7
Protein Similarity:
100
72.1
65.6
81.2
N.A.
100
100
N.A.
73.8
39.8
85.5
37.7
30.7
N.A.
38.7
N.A.
41.3
P-Site Identity:
100
13.3
13.3
20
N.A.
100
100
N.A.
93.3
6.6
13.3
20
6.6
N.A.
20
N.A.
0
P-Site Similarity:
100
13.3
13.3
26.6
N.A.
100
100
N.A.
93.3
26.6
26.6
33.3
26.6
N.A.
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
0
0
8
8
0
8
0
24
0
8
0
8
8
% A
% Cys:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
8
16
0
31
0
0
0
0
0
16
0
0
0
% D
% Glu:
24
0
16
0
39
8
8
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
16
0
24
16
47
16
16
8
31
47
31
24
47
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
39
39
0
0
0
0
0
0
0
8
0
0
39
24
0
% K
% Leu:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
8
0
8
8
8
8
0
0
0
% N
% Pro:
0
0
8
0
0
8
0
0
47
0
31
0
0
0
0
% P
% Gln:
0
8
0
16
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
8
0
16
8
0
0
8
8
8
0
24
8
8
31
8
% R
% Ser:
24
16
39
39
24
24
8
54
16
16
8
16
0
8
8
% S
% Thr:
0
0
0
8
0
8
0
8
0
24
0
0
8
8
8
% T
% Val:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _