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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TWIST2
All Species:
27.51
Human Site:
S5
Identified Species:
50.43
UniProt:
Q8WVJ9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVJ9
NP_476527.1
160
18124
S5
_
_
_
M
E
E
G
S
S
S
P
V
S
P
V
Chimpanzee
Pan troglodytes
Q8MI03
201
20743
S6
_
_
M
M
Q
D
V
S
S
S
P
V
S
P
A
Rhesus Macaque
Macaca mulatta
XP_001103003
192
19946
S9
S
P
A
D
D
S
L
S
N
S
E
E
E
P
D
Dog
Lupus familis
XP_862780
160
17657
S6
_
_
M
M
Q
D
V
S
S
S
P
V
S
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D030
160
18122
S5
_
_
_
M
E
E
G
S
S
S
P
V
S
P
V
Rat
Rattus norvegicus
P97831
160
18106
S5
_
_
_
M
E
E
G
S
S
S
P
V
S
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510876
214
24100
S59
E
G
R
M
E
E
S
S
S
S
P
V
S
P
V
Chicken
Gallus gallus
P79782
183
20177
A10
F
T
M
L
R
P
M
A
A
R
V
L
Y
P
D
Frog
Xenopus laevis
P13903
166
18778
S6
_
_
M
M
Q
E
E
S
S
S
P
V
S
P
V
Zebra Danio
Brachydanio rerio
Q7ZSX3
265
30428
D27
D
D
D
D
F
F
T
D
H
S
S
R
D
H
L
Tiger Blowfish
Takifugu rubipres
Q90YI8
371
40876
T85
I
N
G
V
T
K
E
T
A
S
H
N
A
L
D
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001011637
366
42484
Q137
D
H
S
R
D
Q
E
Q
N
L
Y
L
T
P
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186660
334
37496
G147
D
S
V
M
T
N
G
G
G
V
G
M
K
Y
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.1
59.3
75
N.A.
99.3
100
N.A.
72.9
28.4
78.3
26.4
20.4
N.A.
31.9
N.A.
34.7
Protein Similarity:
100
72.1
65.6
81.2
N.A.
100
100
N.A.
73.8
39.8
85.5
37.7
30.7
N.A.
38.7
N.A.
41.3
P-Site Identity:
100
61.5
20
61.5
N.A.
100
100
N.A.
73.3
6.6
76.9
6.6
6.6
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
76.9
33.3
76.9
N.A.
100
100
N.A.
80
33.3
84.6
13.3
53.3
N.A.
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
8
16
0
0
0
8
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
8
8
16
16
16
0
8
0
0
0
0
8
0
24
% D
% Glu:
8
0
0
0
31
39
24
0
0
0
8
8
8
0
0
% E
% Phe:
8
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
0
0
31
8
8
0
8
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
8
0
8
0
0
8
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
0
0
8
0
0
8
0
0
8
0
16
0
8
16
% L
% Met:
0
0
31
62
0
0
8
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
0
0
0
8
0
0
16
0
0
8
0
0
0
% N
% Pro:
0
8
0
0
0
8
0
0
0
0
54
0
0
77
0
% P
% Gln:
0
0
0
0
24
8
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
8
8
0
0
0
0
8
0
8
0
0
0
% R
% Ser:
8
8
8
0
0
8
8
62
54
77
8
0
54
0
8
% S
% Thr:
0
8
0
0
16
0
8
8
0
0
0
0
8
0
0
% T
% Val:
0
0
8
8
0
0
16
0
0
8
8
54
0
0
39
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
8
8
0
% Y
% Spaces:
47
47
24
0
0
0
0
0
0
0
0
0
0
0
0
% _