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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TWIST2
All Species:
31.82
Human Site:
Y143
Identified Species:
58.33
UniProt:
Q8WVJ9
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVJ9
NP_476527.1
160
18124
Y143
V
A
H
E
R
L
S
Y
A
F
S
V
W
R
M
Chimpanzee
Pan troglodytes
Q8MI03
201
20743
Y184
V
A
H
E
R
L
S
Y
A
F
S
V
W
R
M
Rhesus Macaque
Macaca mulatta
XP_001103003
192
19946
Y175
V
A
H
E
R
L
S
Y
A
F
S
V
W
R
M
Dog
Lupus familis
XP_862780
160
17657
Y143
V
A
H
E
R
L
S
Y
A
F
S
V
W
R
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9D030
160
18122
Y143
V
A
H
E
R
L
S
Y
A
Y
S
V
W
R
M
Rat
Rattus norvegicus
P97831
160
18106
Y143
V
A
H
E
R
L
S
Y
A
F
S
V
W
R
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510876
214
24100
Y197
V
A
H
E
R
L
S
Y
A
F
S
V
W
R
M
Chicken
Gallus gallus
P79782
183
20177
G167
G
G
R
R
D
L
G
G
N
C
L
K
V
R
G
Frog
Xenopus laevis
P13903
166
18778
Y149
V
A
H
E
R
L
S
Y
A
F
S
V
W
R
M
Zebra Danio
Brachydanio rerio
Q7ZSX3
265
30428
I192
L
N
Q
P
K
K
V
I
I
C
H
R
G
T
R
Tiger Blowfish
Takifugu rubipres
Q90YI8
371
40876
V281
D
G
E
T
G
L
M
V
G
A
H
E
V
G
P
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001011637
366
42484
V330
E
R
N
P
R
S
A
V
L
A
A
R
E
I
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186660
334
37496
S316
Y
M
A
H
E
R
L
S
Y
A
F
S
V
W
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.1
59.3
75
N.A.
99.3
100
N.A.
72.9
28.4
78.3
26.4
20.4
N.A.
31.9
N.A.
34.7
Protein Similarity:
100
72.1
65.6
81.2
N.A.
100
100
N.A.
73.8
39.8
85.5
37.7
30.7
N.A.
38.7
N.A.
41.3
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
100
13.3
100
0
6.6
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
13.3
100
13.3
6.6
N.A.
26.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
62
8
0
0
0
8
0
62
24
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
8
62
8
0
0
0
0
0
0
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
54
8
0
0
0
0
% F
% Gly:
8
16
0
0
8
0
8
8
8
0
0
0
8
8
8
% G
% His:
0
0
62
8
0
0
0
0
0
0
16
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
8
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
8
8
0
0
0
0
0
8
0
0
0
% K
% Leu:
8
0
0
0
0
77
8
0
8
0
8
0
0
0
0
% L
% Met:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
62
% M
% Asn:
0
8
8
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
8
8
70
8
0
0
0
0
0
16
0
70
16
% R
% Ser:
0
0
0
0
0
8
62
8
0
0
62
8
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
8
% T
% Val:
62
0
0
0
0
0
8
16
0
0
0
62
24
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
62
8
0
% W
% Tyr:
8
0
0
0
0
0
0
62
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _