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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANKRD49
All Species:
21.52
Human Site:
S75
Identified Species:
36.41
UniProt:
Q8WVL7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVL7
NP_060174.2
239
27290
S75
K
K
M
E
K
D
P
S
R
L
L
L
W
A
A
Chimpanzee
Pan troglodytes
XP_001142795
239
27244
S75
K
K
M
E
K
D
P
S
R
L
L
L
W
A
A
Rhesus Macaque
Macaca mulatta
XP_001089038
239
27228
S75
K
K
M
E
K
D
P
S
K
L
L
L
W
A
A
Dog
Lupus familis
XP_542243
239
27082
S75
K
K
M
E
K
D
P
S
K
L
L
L
W
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE42
238
27093
S74
K
K
M
E
K
D
P
S
K
L
L
L
W
A
A
Rat
Rattus norvegicus
Q8R560
319
36045
E88
L
E
N
L
E
D
L
E
I
I
V
Q
L
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513471
245
27854
E80
N
K
L
K
K
E
P
E
K
L
L
L
W
A
A
Chicken
Gallus gallus
XP_417191
243
27815
E80
K
K
M
E
K
N
P
E
K
L
L
L
W
A
A
Frog
Xenopus laevis
Q4KL97
318
36054
L86
K
L
D
N
L
E
D
L
Q
T
I
I
N
L
K
Zebra Danio
Brachydanio rerio
NP_001017584
218
24287
M60
Q
D
T
P
S
E
L
M
L
W
A
A
E
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609735
215
24225
N57
R
M
I
L
W
A
V
N
E
N
R
I
S
E
V
Honey Bee
Apis mellifera
XP_392305
214
23831
I56
K
E
P
D
A
K
E
I
L
A
A
A
E
N
G
Nematode Worm
Caenorhab. elegans
NP_498030
231
25627
I67
E
K
N
M
E
D
P
I
E
K
W
L
T
A
A
Sea Urchin
Strong. purpuratus
XP_001199821
362
40928
T199
E
D
I
E
N
D
T
T
K
R
I
L
W
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.7
92.8
N.A.
87.4
24.4
N.A.
71.8
69.1
22.3
49.7
N.A.
38.4
35.1
33.8
29.5
Protein Similarity:
100
100
99.5
97
N.A.
94.1
39.8
N.A.
86.1
82.7
38.9
62.7
N.A.
55.2
53.5
46.4
44.4
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
6.6
N.A.
60
80
6.6
0
N.A.
0
6.6
40
40
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
86.6
93.3
33.3
13.3
N.A.
26.6
20
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
0
0
8
15
15
0
65
65
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
8
8
0
58
8
0
0
0
0
0
0
0
0
% D
% Glu:
15
15
0
50
15
22
8
22
15
0
0
0
15
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
15
0
0
0
0
15
8
8
15
15
0
0
0
% I
% Lys:
58
58
0
8
50
8
0
0
43
8
0
0
0
8
15
% K
% Leu:
8
8
8
15
8
0
15
8
15
50
50
65
8
8
0
% L
% Met:
0
8
43
8
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
0
15
8
8
8
0
8
0
8
0
0
8
8
8
% N
% Pro:
0
0
8
8
0
0
58
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
15
8
8
0
0
8
0
% R
% Ser:
0
0
0
0
8
0
0
36
0
0
0
0
8
0
0
% S
% Thr:
0
0
8
0
0
0
8
8
0
8
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
8
0
0
0
0
8
8
0
58
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _