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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TFB1M
All Species:
17.58
Human Site:
S276
Identified Species:
29.74
UniProt:
Q8WVM0
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVM0
NP_057104.2
346
39543
S276
P
E
A
Q
R
L
E
S
T
G
R
L
L
E
L
Chimpanzee
Pan troglodytes
XP_001143221
346
39538
S276
P
E
A
Q
R
L
E
S
T
G
R
L
L
E
L
Rhesus Macaque
Macaca mulatta
XP_001094657
345
39490
N276
P
E
A
Q
R
L
E
N
T
G
R
L
L
E
L
Dog
Lupus familis
XP_533459
345
39285
S276
P
Q
I
H
R
V
E
S
T
G
K
L
L
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZM0
345
38943
S276
P
E
A
Q
R
L
E
S
T
G
R
L
L
Q
L
Rat
Rattus norvegicus
Q811P6
345
39162
S276
P
E
A
Q
R
L
E
S
T
G
R
L
L
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510710
156
18065
P87
K
G
V
G
N
L
F
P
N
T
Q
R
L
E
R
Chicken
Gallus gallus
XP_426165
350
39891
K276
P
E
R
E
R
L
K
K
T
E
Q
L
M
M
A
Frog
Xenopus laevis
Q7T0W5
344
39414
I274
L
F
P
E
E
I
R
I
Q
L
T
E
Q
M
L
Zebra Danio
Brachydanio rerio
NP_001070237
269
30094
A200
R
S
R
L
S
V
M
A
Q
Y
L
T
T
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTM5
330
38082
R261
M
R
Q
K
Y
C
R
R
G
Y
G
T
L
L
P
Honey Bee
Apis mellifera
XP_001121333
420
48497
L350
P
L
E
Y
R
T
E
L
A
Q
M
M
Y
K
L
Nematode Worm
Caenorhab. elegans
P91424
367
41875
L276
P
E
E
L
E
D
E
L
S
D
D
L
L
K
K
Sea Urchin
Strong. purpuratus
XP_001177234
259
29163
L190
G
D
D
Q
R
S
R
L
S
I
M
A
Q
H
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
94.2
88.7
N.A.
84.6
85.2
N.A.
31.7
72.8
69
58
N.A.
47.6
37.3
40.8
48.8
Protein Similarity:
100
100
97.6
94.2
N.A.
91.6
93
N.A.
38.7
86.5
85.5
67.3
N.A.
61.8
53.8
59.6
61.5
P-Site Identity:
100
100
93.3
66.6
N.A.
93.3
93.3
N.A.
20
40
6.6
0
N.A.
6.6
26.6
33.3
20
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
26.6
66.6
20
13.3
N.A.
13.3
40
46.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
36
0
0
0
0
8
8
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
8
0
0
0
8
8
0
0
0
0
% D
% Glu:
0
50
15
15
15
0
58
0
0
8
0
8
0
36
0
% E
% Phe:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
8
0
0
0
0
8
43
8
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
8
0
0
8
0
8
0
8
0
0
0
0
0
% I
% Lys:
8
0
0
8
0
0
8
8
0
0
8
0
0
15
15
% K
% Leu:
8
8
0
15
0
50
0
22
0
8
8
58
65
8
65
% L
% Met:
8
0
0
0
0
0
8
0
0
0
15
8
8
15
0
% M
% Asn:
0
0
0
0
8
0
0
8
8
0
0
0
0
0
0
% N
% Pro:
65
0
8
0
0
0
0
8
0
0
0
0
0
0
8
% P
% Gln:
0
8
8
43
0
0
0
0
15
8
15
0
15
15
0
% Q
% Arg:
8
8
15
0
65
0
22
8
0
0
36
8
0
0
8
% R
% Ser:
0
8
0
0
8
8
0
36
15
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
50
8
8
15
8
0
0
% T
% Val:
0
0
8
0
0
15
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
0
0
0
15
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _