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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TFB1M
All Species:
14.24
Human Site:
S298
Identified Species:
24.1
UniProt:
Q8WVM0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVM0
NP_057104.2
346
39543
S298
R
P
R
Q
L
S
I
S
H
F
K
S
L
C
D
Chimpanzee
Pan troglodytes
XP_001143221
346
39538
S298
R
P
R
Q
L
S
I
S
H
F
K
S
L
C
E
Rhesus Macaque
Macaca mulatta
XP_001094657
345
39490
S298
R
P
R
Q
L
S
I
S
H
F
R
S
L
C
E
Dog
Lupus familis
XP_533459
345
39285
S298
R
P
S
Q
L
S
V
S
H
F
K
S
L
C
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZM0
345
38943
M298
R
P
T
H
L
S
L
M
H
F
K
S
L
C
D
Rat
Rattus norvegicus
Q811P6
345
39162
M298
R
P
T
H
L
S
L
M
H
F
K
S
L
C
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510710
156
18065
R109
A
D
V
D
P
T
L
R
P
G
Q
L
S
I
L
Chicken
Gallus gallus
XP_426165
350
39891
A298
R
P
F
Q
L
T
M
A
H
F
R
N
L
C
N
Frog
Xenopus laevis
Q7T0W5
344
39414
T296
T
L
R
P
T
E
L
T
M
T
H
F
K
K
L
Zebra Danio
Brachydanio rerio
NP_001070237
269
30094
N222
Q
A
F
V
P
K
P
N
V
D
V
G
V
V
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTM5
330
38082
A283
A
E
K
L
F
Q
R
A
E
V
Q
D
T
L
R
Honey Bee
Apis mellifera
XP_001121333
420
48497
E372
R
P
V
E
L
T
I
E
N
I
D
N
L
I
S
Nematode Worm
Caenorhab. elegans
P91424
367
41875
E298
T
S
I
R
L
G
I
E
Q
F
A
D
L
A
E
Sea Urchin
Strong. purpuratus
XP_001177234
259
29163
V212
V
I
P
G
A
A
F
V
P
K
P
Q
I
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
94.2
88.7
N.A.
84.6
85.2
N.A.
31.7
72.8
69
58
N.A.
47.6
37.3
40.8
48.8
Protein Similarity:
100
100
97.6
94.2
N.A.
91.6
93
N.A.
38.7
86.5
85.5
67.3
N.A.
61.8
53.8
59.6
61.5
P-Site Identity:
100
93.3
86.6
86.6
N.A.
73.3
73.3
N.A.
0
53.3
6.6
0
N.A.
0
33.3
26.6
0
P-Site Similarity:
100
100
100
93.3
N.A.
80
80
N.A.
20
93.3
20
20
N.A.
20
60
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
0
0
8
8
0
15
0
0
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% C
% Asp:
0
8
0
8
0
0
0
0
0
8
8
15
0
8
29
% D
% Glu:
0
8
0
8
0
8
0
15
8
0
0
0
0
0
22
% E
% Phe:
0
0
15
0
8
0
8
0
0
58
0
8
0
0
0
% F
% Gly:
0
0
0
8
0
8
0
0
0
8
0
8
0
0
0
% G
% His:
0
0
0
15
0
0
0
0
50
0
8
0
0
0
8
% H
% Ile:
0
8
8
0
0
0
36
0
0
8
0
0
8
15
0
% I
% Lys:
0
0
8
0
0
8
0
0
0
8
36
0
8
8
0
% K
% Leu:
0
8
0
8
65
0
29
0
0
0
0
8
65
8
15
% L
% Met:
0
0
0
0
0
0
8
15
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
0
15
0
0
8
% N
% Pro:
0
58
8
8
15
0
8
0
15
0
8
0
0
0
0
% P
% Gln:
8
0
0
36
0
8
0
0
8
0
15
8
0
0
0
% Q
% Arg:
58
0
29
8
0
0
8
8
0
0
15
0
0
0
8
% R
% Ser:
0
8
8
0
0
43
0
29
0
0
0
43
8
0
8
% S
% Thr:
15
0
15
0
8
22
0
8
0
8
0
0
8
0
0
% T
% Val:
8
0
15
8
0
0
8
8
8
8
8
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _