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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TFB1M All Species: 22.12
Human Site: S302 Identified Species: 37.44
UniProt: Q8WVM0 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WVM0 NP_057104.2 346 39543 S302 L S I S H F K S L C D V Y R K
Chimpanzee Pan troglodytes XP_001143221 346 39538 S302 L S I S H F K S L C E V Y R K
Rhesus Macaque Macaca mulatta XP_001094657 345 39490 S302 L S I S H F R S L C E V Y R R
Dog Lupus familis XP_533459 345 39285 S302 L S V S H F K S L C D V Y R K
Cat Felis silvestris
Mouse Mus musculus Q8JZM0 345 38943 S302 L S L M H F K S L C D V Y R K
Rat Rattus norvegicus Q811P6 345 39162 S302 L S L M H F K S L C D V Y R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510710 156 18065 L113 P T L R P G Q L S I L Q F K S
Chicken Gallus gallus XP_426165 350 39891 N302 L T M A H F R N L C N T Y R K
Frog Xenopus laevis Q7T0W5 344 39414 F300 T E L T M T H F K K L C N V Y
Zebra Danio Brachydanio rerio NP_001070237 269 30094 G226 P K P N V D V G V V H F T P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VTM5 330 38082 D287 F Q R A E V Q D T L R P F E L
Honey Bee Apis mellifera XP_001121333 420 48497 N376 L T I E N I D N L I S A Y K Y
Nematode Worm Caenorhab. elegans P91424 367 41875 D302 L G I E Q F A D L A E G Y N E
Sea Urchin Strong. purpuratus XP_001177234 259 29163 Q216 A A F V P K P Q I D V G V V H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 94.2 88.7 N.A. 84.6 85.2 N.A. 31.7 72.8 69 58 N.A. 47.6 37.3 40.8 48.8
Protein Similarity: 100 100 97.6 94.2 N.A. 91.6 93 N.A. 38.7 86.5 85.5 67.3 N.A. 61.8 53.8 59.6 61.5
P-Site Identity: 100 93.3 80 93.3 N.A. 86.6 86.6 N.A. 0 53.3 0 0 N.A. 0 26.6 33.3 0
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 33.3 93.3 13.3 13.3 N.A. 20 53.3 46.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 15 0 0 8 0 0 8 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 50 0 8 0 0 0 % C
% Asp: 0 0 0 0 0 8 8 15 0 8 29 0 0 0 0 % D
% Glu: 0 8 0 15 8 0 0 0 0 0 22 0 0 8 8 % E
% Phe: 8 0 8 0 0 58 0 8 0 0 0 8 15 0 0 % F
% Gly: 0 8 0 0 0 8 0 8 0 0 0 15 0 0 0 % G
% His: 0 0 0 0 50 0 8 0 0 0 8 0 0 0 8 % H
% Ile: 0 0 36 0 0 8 0 0 8 15 0 0 0 0 0 % I
% Lys: 0 8 0 0 0 8 36 0 8 8 0 0 0 15 43 % K
% Leu: 65 0 29 0 0 0 0 8 65 8 15 0 0 0 15 % L
% Met: 0 0 8 15 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 8 0 0 15 0 0 8 0 8 8 0 % N
% Pro: 15 0 8 0 15 0 8 0 0 0 0 8 0 8 0 % P
% Gln: 0 8 0 0 8 0 15 8 0 0 0 8 0 0 0 % Q
% Arg: 0 0 8 8 0 0 15 0 0 0 8 0 0 50 8 % R
% Ser: 0 43 0 29 0 0 0 43 8 0 8 0 0 0 8 % S
% Thr: 8 22 0 8 0 8 0 0 8 0 0 8 8 0 0 % T
% Val: 0 0 8 8 8 8 8 0 8 8 8 43 8 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 65 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _