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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TFB1M All Species: 26.97
Human Site: T289 Identified Species: 45.64
UniProt: Q8WVM0 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WVM0 NP_057104.2 346 39543 T289 E L A D I D P T L R P R Q L S
Chimpanzee Pan troglodytes XP_001143221 346 39538 T289 E L A D I D P T L R P R Q L S
Rhesus Macaque Macaca mulatta XP_001094657 345 39490 T289 E L A D I D P T L R P R Q L S
Dog Lupus familis XP_533459 345 39285 T289 E L A D V D P T L R P S Q L S
Cat Felis silvestris
Mouse Mus musculus Q8JZM0 345 38943 T289 Q L A D I D P T L R P T H L S
Rat Rattus norvegicus Q811P6 345 39162 T289 Q L A D I D P T L R P T H L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510710 156 18065 M100 E R T K E M L M V A D V D P T
Chicken Gallus gallus XP_426165 350 39891 T289 M A A D V D P T L R P F Q L T
Frog Xenopus laevis Q7T0W5 344 39414 D287 M L R L A D V D P T L R P T E
Zebra Danio Brachydanio rerio NP_001070237 269 30094 P213 V K S C F T I P G Q A F V P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VTM5 330 38082 E274 L P P E D R E E V A E K L F Q
Honey Bee Apis mellifera XP_001121333 420 48497 Q363 K L S D L N P Q T R P V E L T
Nematode Worm Caenorhab. elegans P91424 367 41875 T289 K K C R I D P T T T S I R L G
Sea Urchin Strong. purpuratus XP_001177234 259 29163 C203 H L C Q V K Q C F V I P G A A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 94.2 88.7 N.A. 84.6 85.2 N.A. 31.7 72.8 69 58 N.A. 47.6 37.3 40.8 48.8
Protein Similarity: 100 100 97.6 94.2 N.A. 91.6 93 N.A. 38.7 86.5 85.5 67.3 N.A. 61.8 53.8 59.6 61.5
P-Site Identity: 100 100 100 86.6 N.A. 80 80 N.A. 6.6 66.6 20 0 N.A. 0 40 33.3 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 20 80 20 13.3 N.A. 20 80 46.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 50 0 8 0 0 0 0 15 8 0 0 8 8 % A
% Cys: 0 0 15 8 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 58 8 65 0 8 0 0 8 0 8 0 0 % D
% Glu: 36 0 0 8 8 0 8 8 0 0 8 0 8 0 8 % E
% Phe: 0 0 0 0 8 0 0 0 8 0 0 15 0 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 8 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % H
% Ile: 0 0 0 0 43 0 8 0 0 0 8 8 0 0 0 % I
% Lys: 15 15 0 8 0 8 0 0 0 0 0 8 0 0 8 % K
% Leu: 8 65 0 8 8 0 8 0 50 0 8 0 8 65 0 % L
% Met: 15 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 8 0 0 0 65 8 8 0 58 8 8 15 0 % P
% Gln: 15 0 0 8 0 0 8 8 0 8 0 0 36 0 8 % Q
% Arg: 0 8 8 8 0 8 0 0 0 58 0 29 8 0 0 % R
% Ser: 0 0 15 0 0 0 0 0 0 0 8 8 0 0 43 % S
% Thr: 0 0 8 0 0 8 0 58 15 15 0 15 0 8 22 % T
% Val: 8 0 0 0 22 0 8 0 15 8 0 15 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _