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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCFD1 All Species: 45.45
Human Site: S373 Identified Species: 66.67
UniProt: Q8WVM8 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WVM8 NP_057190.2 642 72380 S373 G E D E G A I S M L S D N T A
Chimpanzee Pan troglodytes XP_509885 713 80661 S444 G E D E G A I S M L S D N T A
Rhesus Macaque Macaca mulatta XP_001107671 704 79791 G446 K S I M G L E G E D E G A I S
Dog Lupus familis XP_537403 636 71870 S367 G E D E G A I S M L S D N T A
Cat Felis silvestris
Mouse Mus musculus Q8BRF7 639 72304 S370 G E D E G A I S M L S D N T A
Rat Rattus norvegicus Q62991 637 72244 S368 G E D E G A I S M L S D N T A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512483 639 72142 S370 G E D E G A I S M L S D N T A
Chicken Gallus gallus XP_421224 720 80613 S451 G E D E G A I S M L S D N T A
Frog Xenopus laevis NP_001086026 632 71276 S363 G E D E G A I S M I S D N T A
Zebra Danio Brachydanio rerio NP_878281 632 71526 S363 G E D D G A I S M L S D N T A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24179 657 74488 S357 G E S D I A F S L V N D T T A
Honey Bee Apis mellifera XP_394325 629 71709 S356 N D S E V A L S M V S N N T A
Nematode Worm Caenorhab. elegans NP_001122697 689 76498 N389 A A D E A L T N V L A D T T A
Sea Urchin Strong. purpuratus XP_001191223 651 73407 S355 E E A I S L L S D T T A K L T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SL48 627 69132 T363 V K S L P E L T E R K K V I D
Baker's Yeast Sacchar. cerevisiae P22213 666 74660 P371 T N I S D L D P N S N N D T V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90 87.5 98.1 N.A. 96.1 95.3 N.A. 94.8 83.8 88.9 86.9 N.A. 56.3 58.8 43.9 65.7
Protein Similarity: 100 90 87.9 98.5 N.A. 97.5 97 N.A. 96.4 86.8 93.7 93.3 N.A. 74.5 76.1 62.9 80
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. 100 100 93.3 93.3 N.A. 46.6 53.3 40 13.3
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 73.3 80 60 26.6
Percent
Protein Identity: N.A. N.A. N.A. 38.3 33 N.A.
Protein Similarity: N.A. N.A. N.A. 59.9 55.7 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 0 7 69 0 0 0 0 7 7 7 0 75 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 63 13 7 0 7 0 7 7 0 69 7 0 7 % D
% Glu: 7 69 0 63 0 7 7 0 13 0 7 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % F
% Gly: 63 0 0 0 63 0 0 7 0 0 0 7 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 13 7 7 0 57 0 0 7 0 0 0 13 0 % I
% Lys: 7 7 0 0 0 0 0 0 0 0 7 7 7 0 0 % K
% Leu: 0 0 0 7 0 25 19 0 7 57 0 0 0 7 0 % L
% Met: 0 0 0 7 0 0 0 0 63 0 0 0 0 0 0 % M
% Asn: 7 7 0 0 0 0 0 7 7 0 13 13 63 0 0 % N
% Pro: 0 0 0 0 7 0 0 7 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % R
% Ser: 0 7 19 7 7 0 0 75 0 7 63 0 0 0 7 % S
% Thr: 7 0 0 0 0 0 7 7 0 7 7 0 13 82 7 % T
% Val: 7 0 0 0 7 0 0 0 7 13 0 0 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _