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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCFD1 All Species: 41.21
Human Site: S384 Identified Species: 60.44
UniProt: Q8WVM8 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WVM8 NP_057190.2 642 72380 S384 D N T A K L T S A V S S L P E
Chimpanzee Pan troglodytes XP_509885 713 80661 S455 D N T A K L T S A V S S L P E
Rhesus Macaque Macaca mulatta XP_001107671 704 79791 D457 G A I S M L S D N T A K L T S
Dog Lupus familis XP_537403 636 71870 S378 D N T A K L T S A V S S L P E
Cat Felis silvestris
Mouse Mus musculus Q8BRF7 639 72304 S381 D N T A K L T S A V S S L P E
Rat Rattus norvegicus Q62991 637 72244 S379 D N T A K L T S A V S S L P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512483 639 72142 S381 D N T A K L T S A V S S L P E
Chicken Gallus gallus XP_421224 720 80613 S462 D N T A K L T S A V S S L P E
Frog Xenopus laevis NP_001086026 632 71276 S374 D N T A K L T S A V S S L P E
Zebra Danio Brachydanio rerio NP_878281 632 71526 S374 D N T A K L T S A V S S L P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24179 657 74488 N368 D T T A R L T N A V N S L P Q
Honey Bee Apis mellifera XP_394325 629 71709 N367 N N T A R L T N A V N N L P Q
Nematode Worm Caenorhab. elegans NP_001122697 689 76498 S400 D T T A K L G S T V M S L P D
Sea Urchin Strong. purpuratus XP_001191223 651 73407 S366 A K L T S A V S S L P E L L E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SL48 627 69132 N374 K V I D K H T N I A T A L L G
Baker's Yeast Sacchar. cerevisiae P22213 666 74660 E382 N D T V Q I Q E V V K K L P E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90 87.5 98.1 N.A. 96.1 95.3 N.A. 94.8 83.8 88.9 86.9 N.A. 56.3 58.8 43.9 65.7
Protein Similarity: 100 90 87.9 98.5 N.A. 97.5 97 N.A. 96.4 86.8 93.7 93.3 N.A. 74.5 76.1 62.9 80
P-Site Identity: 100 100 13.3 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 66.6 60 66.6 20
P-Site Similarity: 100 100 33.3 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 93.3 100 73.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. 38.3 33 N.A.
Protein Similarity: N.A. N.A. N.A. 59.9 55.7 N.A.
P-Site Identity: N.A. N.A. N.A. 20 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 75 0 7 0 0 69 7 7 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 69 7 0 7 0 0 0 7 0 0 0 0 0 0 7 % D
% Glu: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 69 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % G
% His: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 13 0 0 7 0 0 7 0 0 0 0 0 0 % I
% Lys: 7 7 0 0 69 0 0 0 0 0 7 13 0 0 0 % K
% Leu: 0 0 7 0 0 82 0 0 0 7 0 0 100 13 0 % L
% Met: 0 0 0 0 7 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 13 63 0 0 0 0 0 19 7 0 13 7 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 7 0 0 82 0 % P
% Gln: 0 0 0 0 7 0 7 0 0 0 0 0 0 0 13 % Q
% Arg: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 7 7 0 7 69 7 0 57 69 0 0 7 % S
% Thr: 0 13 82 7 0 0 75 0 7 7 7 0 0 7 0 % T
% Val: 0 7 0 7 0 0 7 0 7 82 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _