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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCFD1 All Species: 13.64
Human Site: S78 Identified Species: 20
UniProt: Q8WVM8 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WVM8 NP_057190.2 642 72380 S78 T L H L L L H S D R D P I P D
Chimpanzee Pan troglodytes XP_509885 713 80661 S149 T L H L L L H S D R D P I P D
Rhesus Macaque Macaca mulatta XP_001107671 704 79791 S158 T L H L L L H S D R D P I P D
Dog Lupus familis XP_537403 636 71870 P76 L L H S D R D P I P D V P A V
Cat Felis silvestris
Mouse Mus musculus Q8BRF7 639 72304 D76 L H L L L H S D R D P I P D V
Rat Rattus norvegicus Q62991 637 72244 D76 L L L H S D R D P I R D V P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512483 639 72142 D76 L H L L L H S D R D P I P D V
Chicken Gallus gallus XP_421224 720 80613 S156 T L H L L L H S D R D P I P D
Frog Xenopus laevis NP_001086026 632 71276 P77 R D A I P D V P A V Y F V M P
Zebra Danio Brachydanio rerio NP_878281 632 71526 V76 D R D P I P D V P A I Y F I M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24179 657 74488 F80 P D V P A I Y F C L P T D E N
Honey Bee Apis mellifera XP_394325 629 71709 P76 R D S I P E V P A I Y F C A P
Nematode Worm Caenorhab. elegans NP_001122697 689 76498 A99 T L H L L I G A R R E P L T D
Sea Urchin Strong. purpuratus XP_001191223 651 73407 N77 F V L P T E E N V Q R I C Q D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SL48 627 69132 F82 H D V P A V Y F V Q P T E S N
Baker's Yeast Sacchar. cerevisiae P22213 666 74660 Q88 T V H S L I K Q D R S P L P D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90 87.5 98.1 N.A. 96.1 95.3 N.A. 94.8 83.8 88.9 86.9 N.A. 56.3 58.8 43.9 65.7
Protein Similarity: 100 90 87.9 98.5 N.A. 97.5 97 N.A. 96.4 86.8 93.7 93.3 N.A. 74.5 76.1 62.9 80
P-Site Identity: 100 100 100 20 N.A. 13.3 13.3 N.A. 13.3 100 0 0 N.A. 0 0 53.3 6.6
P-Site Similarity: 100 100 100 20 N.A. 13.3 20 N.A. 13.3 100 13.3 6.6 N.A. 20 6.6 80 26.6
Percent
Protein Identity: N.A. N.A. N.A. 38.3 33 N.A.
Protein Similarity: N.A. N.A. N.A. 59.9 55.7 N.A.
P-Site Identity: N.A. N.A. N.A. 0 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 13 0 0 7 13 7 0 0 0 13 7 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 0 13 0 0 % C
% Asp: 7 25 7 0 7 13 13 19 32 13 32 7 7 13 44 % D
% Glu: 0 0 0 0 0 13 7 0 0 0 7 0 7 7 0 % E
% Phe: 7 0 0 0 0 0 0 13 0 0 0 13 7 0 0 % F
% Gly: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % G
% His: 7 13 44 7 0 13 25 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 13 7 19 0 0 7 13 7 19 25 7 0 % I
% Lys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % K
% Leu: 25 44 25 44 50 25 0 0 0 7 0 0 13 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 7 % M
% Asn: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 13 % N
% Pro: 7 0 0 25 13 7 0 19 13 7 25 38 19 38 13 % P
% Gln: 0 0 0 0 0 0 0 7 0 13 0 0 0 7 0 % Q
% Arg: 13 7 0 0 0 7 7 0 19 38 13 0 0 0 0 % R
% Ser: 0 0 7 13 7 0 13 25 0 0 7 0 0 7 0 % S
% Thr: 38 0 0 0 7 0 0 0 0 0 0 13 0 7 0 % T
% Val: 0 13 13 0 0 7 13 7 13 7 0 7 13 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 13 0 0 0 13 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _