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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCFD1 All Species: 53.94
Human Site: Y604 Identified Species: 79.11
UniProt: Q8WVM8 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WVM8 NP_057190.2 642 72380 Y604 G G G N Y I E Y Q N L V D Y I
Chimpanzee Pan troglodytes XP_509885 713 80661 Y675 G G G N Y I E Y Q N L V D Y I
Rhesus Macaque Macaca mulatta XP_001107671 704 79791 N666 S S V P R N K N P F Q E A I V
Dog Lupus familis XP_537403 636 71870 Y598 G G G N Y I E Y Q N L V D Y I
Cat Felis silvestris
Mouse Mus musculus Q8BRF7 639 72304 Y601 G G G N Y I E Y Q N L V D Y I
Rat Rattus norvegicus Q62991 637 72244 Y599 G G G N Y I E Y Q N L V D Y I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512483 639 72142 Y601 G G G N Y I E Y Q N L V D Y I
Chicken Gallus gallus XP_421224 720 80613 Y682 G G G N Y I E Y Q N L I D Y I
Frog Xenopus laevis NP_001086026 632 71276 Y594 G G G N Y I E Y Q N L V D Y I
Zebra Danio Brachydanio rerio NP_878281 632 71526 Y594 G G G N Y I E Y Q N L V D Y T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24179 657 74488 Y607 G G G N Y I E Y Q N L V D F I
Honey Bee Apis mellifera XP_394325 629 71709 Y584 G G G N Y I E Y Q N L V D Y V
Nematode Worm Caenorhab. elegans NP_001122697 689 76498 Y649 G G G N Y V E Y Q N L V D Y G
Sea Urchin Strong. purpuratus XP_001191223 651 73407 Y585 G G G N Y I E Y Q N L L D Y V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SL48 627 69132 I589 Q L T V K N V I Y G A T E I L
Baker's Yeast Sacchar. cerevisiae P22213 666 74660 N621 G N Y L E Y Q N L Q E W A H S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90 87.5 98.1 N.A. 96.1 95.3 N.A. 94.8 83.8 88.9 86.9 N.A. 56.3 58.8 43.9 65.7
Protein Similarity: 100 90 87.9 98.5 N.A. 97.5 97 N.A. 96.4 86.8 93.7 93.3 N.A. 74.5 76.1 62.9 80
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 100 93.3 100 93.3 N.A. 93.3 93.3 86.6 86.6
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. 100 100 100 93.3 N.A. 100 100 93.3 100
Percent
Protein Identity: N.A. N.A. N.A. 38.3 33 N.A.
Protein Similarity: N.A. N.A. N.A. 59.9 55.7 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 7 0 13 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 82 0 0 % D
% Glu: 0 0 0 0 7 0 82 0 0 0 7 7 7 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 7 0 0 0 7 0 % F
% Gly: 88 82 82 0 0 0 0 0 0 7 0 0 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 0 0 0 0 0 75 0 7 0 0 0 7 0 13 57 % I
% Lys: 0 0 0 0 7 0 7 0 0 0 0 0 0 0 0 % K
% Leu: 0 7 0 7 0 0 0 0 7 0 82 7 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 82 0 13 0 13 0 82 0 0 0 0 0 % N
% Pro: 0 0 0 7 0 0 0 0 7 0 0 0 0 0 0 % P
% Gln: 7 0 0 0 0 0 7 0 82 7 7 0 0 0 0 % Q
% Arg: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 7 7 0 0 0 0 0 0 0 0 0 0 0 0 7 % S
% Thr: 0 0 7 0 0 0 0 0 0 0 0 7 0 0 7 % T
% Val: 0 0 7 7 0 7 7 0 0 0 0 69 0 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % W
% Tyr: 0 0 7 0 82 7 0 82 7 0 0 0 0 75 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _